UW revision factitous laxatives Flashcards
Factitious. Behavioural characteristics? 2
Intentional falsification of illness: feigninng illness, self-induced illness, exacerbation of preexisting illness
Factitious. CP? 4
Overt, dramatic symptoms
Frequent visits for medical care
Patient possibly refusing consent to release records or tampering with test samples
More common in healthcare workers (have access to drugs)
Factitious. Dx? 4
Direct obervation or discovery or medical supplies
Confirmatory testing (sulfonylurea screen, sool laxative screen)
Medical record review
prie klausimo buvo stool osmolality measure (dar yra stool electorlytes or stool osmotic gap)
Factitious. Stool osmotic gap formula?
290 - 2x(stool Na + stool K)
Factitious. Stool osmotic gap < 50?
secretory diarrhea
Factitious. Stool osmotic gap 50-125?
indeterminate
Factitious. Stool osmotic gap >125?
Osmotic diarrhea
SECRETORY DIARRHEA. Causes? 4
Toxins (eg Vibrio cholera), hormones (produced by VIPomas), congenital disorders of ion transport (eg CF), or bile acids (in postsurgical patients)
SECRETORY DIARRHEA. CP?2
Low osmotic stool gap
Diarrhea persist during periods of fasting (eg diarrhea during night)
OSMOTIC DIARRHEA. Causes?
Osmotic laxatives
Causative substances = milk in a patient with lactose intolerance
OSMOTIC DIARRHEA. CP?
Diarrhea presents only then substance is consumed, but not present when fasting.
Secretory diarrhea can occur after bowel resection or cholecystectomy - unabsorbed bile acids reach the colon and result in the direct stimulation of luminal ion chales.
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