UTI Flashcards
Difference between relapse and reinfection in UTI?
Relapse = same infection w/ same species occuring <4 weeks post treatment
Reinfection = different species >2 weeks after treatment completion
Common specieis involved in UTI?
E. Coli
K pneumonia
proteus mirabilis
S saprophyticus
signs of UTI in higher region (ie pylonephritis)
Flank pain, fever, nasuea and vomitting
What is a complicated UTI?
Abnormal GU tract due to structural or functional abnormalities (includes catheter use)
Basically every single UTI in men
What product is associated with increased rates of recurrent UTI in women?
Spermcide use
Acute uncomplicated UTI treatment
first line
TMP/SMX or TMP F3D
Nitrofurantoin F5D
Fosfomycin 1 dose
second line
Cipro, nor, levo floxacin F3D
Cephelexin F7D
Pylenophritis non severe treatment
Cipro or levoflox F7-14D
Second line
Amoxi/clav or TMP/SMX or TMP F10-14D
Severe pylonephritis or complicated UTI
IV aminoglycoside (gentamycin, tobramycin, amikacin) and consider adding ampicillin IV
Consider step down if mild symptoms
total treatment for 10-14 days
Second line
cipro or levo IV or third gen cephalos IV with maybe aminoglycoside iv (F10-14D) or carbapenem IV (7-14 days) or pipercillin-tazobactam (F7-10d)
Mild to moderate complicated UTI treatments
Firstline ALL 7-10 days
same as uncomplicated options but instead of fosfomycin you add cipro or levo
Second line ALL 7-10 days
Amoxi/clav
Cephalexin
Cefixime
Acute prosttatis treatments
Aminoglycoside IV +- cloxacillin IV +- Ampicillin IV
Second lline
Ciproflox or levoflox F4W
TMP/SMX F4-6W
Chronic prostatitis treatment
Cipro or levo F4-6W
Second line
SMX/TMP F4-6W
definition of recurrent UTI
> = 2 episodes of acute cytitis within 6 months or >3 in a year
Options in pregnancy
Amoxi, amoxiclav, cephalexin, fosfomycin, nitrofurantoin (except near term), cefrtiaxone, FQ (risk of disorders), TMP or TMPSMX avoided in first trimester and last 6 weeks