Fungal infections general Flashcards
Vulvovaginal candidiasis common presentation?
Thick white cottage cheese-like discharge, dysuria, irritation
Do you treat asyptomatic vulvovaginal candidiasis?
Nope
Uncomplicated vulvovaginal candidiasis treatment options?
Clotrimazole 1% cream 7-14 days
Micronazole 100mg suppository once daily for 7 days, 200mg is for 3 days, 1200 for 1 day
Fluconazole 150mg orally once daily
Treatment of complicated vulvovaginal candidiasis
Topical Azole F7-14D
Fluconazole 150mg PO twice (one dose followed by a dose 3 days later)
Non-C. albicans infection:
7-14 days with nonfluconazole azole (topical or oral)
Boric acid 600mg vaginally OD F3W
Onychomycosis classifications
Distal lateral subungual onychomycosis = most common, nail bed and underside of nail
Superficial white onychomycosis = surface of nail, white islands in nail
Proximal subungal onychomycosis = affects the part of nail closes to the joint (idk dude thats a bad description but imagine it fucking up the area around where the nail grows out from)
When to use topicals in onychomycosis?
Distal and lateral subungual with minimal involvment
Superficial white onychomycosis
CI to orals
Onychomycosis topicals?
efinaconazole 10% for 48 weeks
Circlopirox F48W
Oral antifungals for onychomycosis?
Terbinafine 250mg OD F3M -> agent of choice for dermatophytes
Itraconazole 200mg once daily F3M (non dermatophytes)
200mg BID F1W every month for 3 pulses for toenails, 2 pulses for fingernails