Uterine Leomyomata Flashcards

0
Q

Exam findings consistent with uterine fibroids? Consistent with ovarian mass?

A

Irregular midline mass continuous with the cervix

Lateral mass apart from the cervix

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1
Q

Most common reason for hysterectomy in the US? Most common symptom? Hysterectomy performed in which patients?

A

Symptomatic uterine fibroids; menorrhagia;

Systematic fibroids that are refractory to medical therapy

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2
Q

Patient with menorrhagia - consider?

Metrorrhagia?

A

Fibroids

Endometrial hyperplasia, endometrial polyp, uterine cancer, uterine fibroids

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3
Q

Type of fibroid that impinges on Uterine cavity?

A

Submucosal

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4
Q

Types of fibroids?

A
  1. Subserosal
  2. Intramural
  3. Sub mucosal
  4. Pedunculated
  5. Cervical
  6. Prolapsed
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5
Q

Carneous degeneration? aka?

A

Changes of the fibroid due to rapid growth – Center becomes a red and causes pain

Red degeneration

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6
Q

Signs of a leiomyosarcoma? Risk factor?

A

Rapid growth (increase of more than six weeks gestational size in one year)

Radiation the pelvis

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7
Q

Signs of prolapsed fibroid?

A

Labor-like contractions and pain

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8
Q

Differential diagnosis for fibroids?

A
  1. Ovarian masses
  2. Tubo-ovarian masses
  3. Pelvic kidney
  4. Endometrioma
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9
Q

Initial treatment for fibroids?

Other tx?

A

NSAIDs or progestin

  1. GnRH agonist
  2. Hysterectomy if future pregnancy undesired
  3. Myomectomy if future pregnancy desired
  4. Uterine artery embolization
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10
Q

GnRH agonist – used for? Time course? downside? Use when?

A

GnRH agonist (take three months but after cessation, fibroids will regrow)

Tumor shrinkage or correction of anemia prior to operative treatment

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11
Q

Uterine artery embolization?

A

Cannulizing femoral artery and infusing embolization particles into uterine arteries (to float into fibroid vessels) leading to fibroid infarction

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12
Q

Type of fibroids associated with recurrent abortion? Why?

A

Submucosal – altered endometrium, and insufficient vasculature

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13
Q

Fibroids may present with severe pain if?

A

Twists on pedicle

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14
Q

Patient with myomectomy gets pregnant – concern?

A

Uterine rupture – delivered via C-section

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15
Q

Progestins and GnRH agonists stop being effective for fibroids when?

A

When Leiomyomas degenerate into leiomyosarcomas