Parvovirus Infection Pregnancy

Question 0

Pregnant patients with negative IgG and negative IgM for parvovirus – when to still be concerned?

Answer 0

If less than 20 days from possible exposure; repeat test in 1-2 weeks

Question 1

Adult parvovirus signs/symptoms?

Answer 1

Malaise, arthralgias/myalgias, reticular (lacy) rash

Question 2

Parvovirus – type of virus?

Answer 2

Single-stranded DNA virus

Question 3

Fetal hydrops?
Associated with?
Gestational age most at risk?

Answer 3

Excess fluid and body cavities (ascites, skin edema, pericardial effusion, pleural effusion)

Hydramnios

Less than 20 weeks

Question 4

Sinusoidal heart rate pattern? Indicates?

Answer 4

Fetal heart rate pattern with 3-5 sine waves per minute

Severe fetal anemia or asphyxia

Question 5

Patients infected with parvovirus B 19 – how to follow?

Answer 5

Weekly fetal ultrasounds for 10 weeks to assess for fetal hydrops

Question 6

Causes of hydramnios?

Answer 6

1. Mother - Multiple gestation, maternal diabetes
2. Immune - Isoimmunization, fetal non-immune hydrops, syphilis
3. CNS or G.I. malformations
4. Chromosomal abnormalities