Anemia In Pregnancy

Question 0

Pregnant patients with mild anemia and no risk factors for hemoglobinopathies – treatment? Reassess when? Risk factors for hemoglobinopathies? If anemia persists?

Answer 0

Trial of iron supplements; 3-4 weeks;

African-American, Southeast Asian, Mediterranean

Ferritin, hemoglobin electrophoresis

Question 1

Anemia in pregnancy defined as? Severe if? Most common cause?

Answer 1

Hemoglobin <10.5; under 7

Iron deficiency

Question 2

Life expectancy for beta thalassemia major?

Answer 2

20s

Question 3

Sickle cell disease in pregnancy (Regarding mother)? Crises can mimic?

Answer 3

1. More intense anemia
2. more frequent crises (Avoid dehydration)
3. more frequent infections
4. pulmonary complications
5. Preterm labor

Crises may mimic ectopic pregnancy, placental abruption, pyelonephritis, appendicitis etc.

Question 4

Pregnant patients with sickle cell – increased fetal risk for? Management?

Answer 4

IUGR, perinatal mortality; serial ultrasonography

Question 5

Macrocytic anemia – cause in pregnancy?

Answer 5

Folate deficiency >B12 deficiency

Question 6

Drug causes of G6PD deficiency?

Answer 6

Nitrofurantoin, sulfonamides, antimalarials

Question 7

Signs of G6PD deficiency?

Answer 7

Jaundice, dark colored urine, fatigue

Question 8

Signs of acute leukemia? Effects on pregnancy?

Treatment? Effect on the pregnancy?

Answer 8

Fever, pancytopenia; preterm labor, spontaneous abortion, stillbirth

Chemotherapy; IUGR