Urticaria Flashcards
common molecular structure shared by many pathogens
pathogen-associated molecular protein (PAMP)
involves dilation of vascular structures in the superficial dermis
urticaria
originates from the deeper dermis and subcutaneous tissue
angioedema
well-circumscribed wheals with erythematous raised serpiginous borders and blanched centers
urticaria
dramatic swelling with more pain than puritus and minimal erythema
angioderma
linear wheal with surrounding erythema at the site of a brisk stroke with a firm object
dermographism
presents in response to a sustained stimulus
pressure urticaria
most common site for angioderma
periorbital or perioral
angioderma in upper repiratory tract may be life-threatening due to _____
transient laryngeal obstruction
perivenular infiltrate consists of
lymphocytes
monocytes
eosinophils
neutrophils
best evidence for igE and mast cell involvement in urticaria and angioderma
cold urticaria
mutation in SERPING1 gene = C1NH deficiency
hereditary angioderma
precipitated by rise in core body temperature
cholinergic urticaria
precipitated by exertion
exercise-induced anaphylaxis
angioedema without urticaria that can be idiopathic or due to C1 inhibitor deficiency
isolated angioedema