Lung Cancer, Head and Neck, CUP, Oncologic Emergencies

Question 1

how to distinguish SCLC from NSCLC

Answer 1

CD56
neural cell adhesion molecule (NCAM)
synaptophysin
chromogranin

Question 2

marker for adenocarcinoma

Answer 2

thyroid transcription factor 1

napsin-A

Question 3

marker for squamous

Answer 3

p40 or p63

mucin stains

Question 4

presenting finding or first sign of recurrence (SCLC)

Answer 4

paraneoplastic syndromes

Question 5

most common life-threatening metabolic complication of malignancy

Answer 5

PTH-related peptide

Question 6

most significant risk factor for head and neck cancer

Answer 6

alcohol and tobacco use

Question 7

etiologic agent for oral cancers

Answer 7

smokeless tobacco

Question 8

oropharyngeal tumor - generally caused by what infection

Answer 8

HPV

Question 9

first sign of HPV-related tumor

Answer 9

neck lymphadenopathy

Question 10

common site of CUP presentation

Answer 10

liver

Question 11

responsible for the majority of SVCS cases

Answer 11

lung cancer
lymphoma
metastatic tumors

Question 12

initial manifestation of Behcet’s syndrome

Answer 12

SVCS

Question 13

SVCS is milder if obstruction is above

Answer 13

azygos vein

Question 14

most significant chest radiographic finding of SVCS

Answer 14

widening of superior mediastinum, right side

Question 15

malignant pericardial disease most frequently seen in

Answer 15

lung cancer
breast cancer
leukemia
lymphoma

Question 16

pericardial metastasis common symptoms

Answer 16

dyspnea
cough
chest pain
orthopnea
weakness

Question 17

most frequent physical findings or pericardial metastasis

Answer 17

pleural effusion
sinus tachycardia
jugular venous distention
hepatomegaly
peripheral edema
cyanosis

Question 18

most common symptom of intestinal obstruction

Answer 18

pain

Question 19

measurement of acute cecal dilation that is considered surgical emergency

Answer 19

> 12-24cm

Question 20

most common symptom of urinary obstruction

Answer 20

flank pain

Question 21

common clinical problem causing malignant biliary obstruction

Answer 21

primary carcinoma of:
pancreas
ampulla of vater
bile duct
liver

metastatic disease:
periductal lymph nodes
liver parenchyma

Question 22

most common metastatic tumors causing biliary obstruction

Answer 22

gastric
colon
breast
lung

Question 23

first manifestation of malignancy in MSCC

Answer 23

epidural tumor

Question 24

most common cause of MSCC

Answer 24

lung cancer

Question 25

most common site of MSCC

Answer 25

thoracic

Question 26

most common initial symptom of MSCC

Answer 26

localized back pain

tenderness

Question 27

tingling electric sensation down the back and upper & lower limbs upon flexing or extending the neck

Answer 27

Lhermitte’s sign

Question 28

earliest radiologic finding of vertebral tumor

Answer 28

erosion of pedicles “the winking owl” sign

Question 29

initial treatment of choice for SCC

Answer 29

radiotherapy with glucocorticoids

Question 30

most common paraneoplastic syndrome

Answer 30

hypercalcemia