Lung Cancer, Head and Neck, CUP, Oncologic Emergencies Flashcards

1
Q

how to distinguish SCLC from NSCLC

A

CD56
neural cell adhesion molecule (NCAM)
synaptophysin
chromogranin

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2
Q

marker for adenocarcinoma

A

thyroid transcription factor 1

napsin-A

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3
Q

marker for squamous

A

p40 or p63

mucin stains

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4
Q

presenting finding or first sign of recurrence (SCLC)

A

paraneoplastic syndromes

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5
Q

most common life-threatening metabolic complication of malignancy

A

PTH-related peptide

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6
Q

most significant risk factor for head and neck cancer

A

alcohol and tobacco use

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7
Q

etiologic agent for oral cancers

A

smokeless tobacco

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8
Q

oropharyngeal tumor - generally caused by what infection

A

HPV

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9
Q

first sign of HPV-related tumor

A

neck lymphadenopathy

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10
Q

common site of CUP presentation

A

liver

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11
Q

responsible for the majority of SVCS cases

A

lung cancer
lymphoma
metastatic tumors

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12
Q

initial manifestation of Behcet’s syndrome

A

SVCS

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13
Q

SVCS is milder if obstruction is above

A

azygos vein

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14
Q

most significant chest radiographic finding of SVCS

A

widening of superior mediastinum, right side

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15
Q

malignant pericardial disease most frequently seen in

A

lung cancer
breast cancer
leukemia
lymphoma

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16
Q

pericardial metastasis common symptoms

A
dyspnea
cough
chest pain
orthopnea
weakness
17
Q

most frequent physical findings or pericardial metastasis

A
pleural effusion
sinus tachycardia
jugular venous distention
hepatomegaly
peripheral edema
cyanosis
18
Q

most common symptom of intestinal obstruction

19
Q

measurement of acute cecal dilation that is considered surgical emergency

20
Q

most common symptom of urinary obstruction

A

flank pain

21
Q

common clinical problem causing malignant biliary obstruction

A
primary carcinoma of:
pancreas
ampulla of vater
bile duct
liver

metastatic disease:
periductal lymph nodes
liver parenchyma

22
Q

most common metastatic tumors causing biliary obstruction

A

gastric
colon
breast
lung

23
Q

first manifestation of malignancy in MSCC

A

epidural tumor

24
Q

most common cause of MSCC

A

lung cancer

25
most common site of MSCC
thoracic
26
most common initial symptom of MSCC
localized back pain | tenderness
27
tingling electric sensation down the back and upper & lower limbs upon flexing or extending the neck
Lhermitte's sign
28
earliest radiologic finding of vertebral tumor
erosion of pedicles "the winking owl" sign
29
initial treatment of choice for SCC
radiotherapy with glucocorticoids
30
most common paraneoplastic syndrome
hypercalcemia