urologic problems: pyelonephritis Flashcards

1
Q

lithos

A

stone

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2
Q

calculi

A

something accidental that doesn’t belong in body (ex: stone)

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3
Q

UTI: protective factors

A

acidic pH
presence of urea
urine is uni-directional
immune system
*men: prostatic secretions
*women: urethral gland secretions

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4
Q

why are women at higher risk than males for UTIs?

A

shorter urethra
urethral opening closer to anus (bacteria)

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5
Q

UTI: risk factors

A

-CAUTIs
-female; perineal irritation
-age
-pregnancy
-sex
-urinary obstruction or reflux
-immobility
-incontinence (urine+stool)
-decreased cognition
-bad personal hygiene

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6
Q

consideration with nursing homes relative to UTIs

A

50% have bacteriuria
*dont treat with abx
*expected finding

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7
Q

order of the spread of a UTI

A

(BOTTOM)
1. contaminated perineum
2. urethra
3. bladder (cystitis: bladder infection)
4. ureter
5. kidney (pyelonephritis)
(TOP)

*goes up in ascending pattern

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8
Q

upper UTI

A

pyelonephritis: inflammation/infection of kidney

inflammatory response –> kidney infection –> kidney failure

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9
Q

cause of pyelonephritis/upper UTI

A

ascending infection with E. coli
bloodstream infection

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10
Q

major risk factor of an upper UTI

A

pregnancy

fetus can block ureters, causing urinary stasis, thus infection occurs

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11
Q

upper UTI: clinical manifestations

A

sudden onset of fever, chills, CVA tenderness

lower UTI S/S
-dysuria
-frequency
-urgency

N/V, anorexia

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12
Q

complication of a UTI

A

urosepsis

untreated UTI spreads through urinary tract to kidney and causes sepsis

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13
Q

who is at risk for urosepsis?

A

serious systemic (inflammatory) response to a UTI

-elderly patients
-diabetics
-immunosuppressed patients

DEADLY, but treatable

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14
Q

UTI treatment depends on

A

upper vs. lower UTI
complications
pregnancy
culture and sensitivity

*upper is treated more aggressively than lower

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15
Q

types of abx for community-acquired infections

A

single dose
short course (3 days)
conventional (7-14) ** more for pt who have a reoccurrence of UTIs

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16
Q

first line antibiotics for UTI

A

ciprofloxacin

17
Q

MOA ciprofloxacin

A

inhibits bacterial reproduction and works locally at infection site

18
Q

ciprofloxacin CONSIDERATIONS

A

BLACK BOX WARNING: risk of tendon rupturE/bone pain

NOT for <18 or >60

19
Q

what do we give if we cannot give ciprofloxacin

A

vancomycin