Urinary Tract Infections

Question 1

Which UTI antibiotic should be avoided in the first trimester of pregnancy?

Answer 1

Trimethoprim.
As trimethoprim is a folate antagonist it should be avoided in the first trimester - this is the time when the neural tube forms and there is a risk of teratogenicity.

Question 2

Which UTI antibiotic should be avoided near full term pregnancy?

Answer 2

Nitrofurantoin.

There is a risk of causing neonatal haemolysis.