Urinary System and Opthalmic Diseases Flashcards
What are the functions of the Kidneys?
- produce urine: excretion
- maintain homeostasis: blood filtration, reabsorption, secretion; fluid balance regulation; acid-base balance regulation; hormone production
What is Feline Cystitis?
nonmalignant inflammatory condition that occurs frequently in cats
What is the cause of Feline Cystitis?
- cause is unknown
- multi factorial
- not caused by bacteria
What is the Signalment of Feline Cystitis?
- cats 2-6 yrs old
- occurs more in males than females
What are C/S of Feline Cystitis?
- pollakuria
- hematuria
- dysuria
- periuria (inappropriate urination)
How do you diagnose Feline Cystitis?
- urinalysis/culture: to rule out bacteria as cause
- radiographs: to rule out calculi. contrast studies may show thickened bladder wall
How do you treat Feline Cystitis?
- avoid unnecessary use of antibiotics
- change diet to produce dilute urine
- reduce stress from other cats, kids, etc: provide hiding places, pheromonotherapy
- behavior modification drugs: amitrypitilline, clomipramine
- glycosaminoglycan replacement: cosequin, adequan
What is Client Info for Feline Cystitis?
- disease is self limiting: resolution of c/s in 7-10 days
- may be reccuring problem
- no definitive cure
- reduce stress
What are the natural defense mechanisms of the Kidneys?
- frequent voiding of urine
- urethral and ureteral peristalsis
- glycosaminoglycans in the surface mucosal layer
- pH
- constituents of urine
What is the cause of Canine Bacterial Cystitis?
ascending bacteria up the urethra
What are the C/S of Canine Bacterial Cystitis?
- increased frequency of urination
- hematuria
- dysuria
- cloudy urine, abnormal color
- frequent licking of vaginal/urethral area
How do you diagnose Canine Bacterial Cystitis?
- urinalysis: increased WBC’s and bacteria
- urine culture and sensitivity: collect by cytocentesis
How do you treat Canine Bacterial Cystitis?
- antibiotics according to sensitivity: acute infections (10-14d), subsequent infections(4-6 weeks)
- avoid trauma to urinary tract during surgery
- indwelling catheters should be closed system
What is Client Info for Canine Bacterial Cystitis?
- can resolve without treatment
- give antibiotics as directed
- prostate may be source of recurring infections
- urine cultures should be repeated
What are the 2 most common types of urethral blockages?
- uroliths
- urethral plugs
What are Uroliths?
composed of minerals and a small amount of matrix
What are Urethral Plugs?
composed of small amount of minerals and large amount of matrix
What are the 3 different types of struvites that occur in cats?
- sterile urocystoliths
- infection-induced urocystolith
- matrix-struvite urethral plug
What are C/S of Feline Uroliths and Urethral Plugs?
- hematuria
- dysuria
- periuria
- anorexia, vomiting
- collapse, death
- non-specific signs: hiding, crying while urinating, frequent trips to litter box
How do you diagnose Feline Uroliths and Urethral Plugs?
- palpation of bladder: full and tight
- radiographs: double contrast study may be indicated
- ultrasound:locate position of urolith
- urolith analysis: necessary to determine type
- EKG: atrial standstill, bradycardia, hyperkalemia
What is the Medical Treatment (chronic, non obstructed) of Feline Uroliths and Urethral Plugs?
- dissolve struvite uroliths by acidifying urine and feeding diet low in Mg
- cystotomy to remove stones
- antibiotics according to culture/sensitivity
What is the Medical Treatment (obstructed) of Feline Uroliths and Urethral Plugs?
- this is a medical emergency!
- anesthetize (short acting)
- pass tom cat catheter and back flush
- sew catheter in place for 1-3 days, using closed system
What is the Medical Treatment (chronic obstructers) for Feline Uroliths and Urethral Plugs?
- perineal urethrostomy
- goal of surgery is to decrease the likelihood of life-threatening obstruction
What are C/S of Canine Urolithiasis?
- pollakiuria
- dysuria
- hematuria
How do you diagnose Canine Urolithiasis?
- urinalysis (crystalluria, hematuria, increased bacteria)
- radiographs (double contrast study if necessary)
How do you treat Canine Urolithiasis?
- change diet
- acidify urine (urinary acidifiers)
- increase urine output ( add salt to diet)
- antibiotics for bacterial infection
- surgical removal (calcium oxalate)
- stone analysis is vital for appropriate treatment
What is Client Info for Canine Urolithiasis?
- special diet may be required for life
- table scraps/treats should be limited
- long term antibiotics may be required
- uroliths may recur at any time
- always provide plenty of water
- allow plenty of bathroom time and frequency
Renal Failure is due to what?
- decreased blood flow
- damage to nephron and glomerular fitration declines resulting in azotemia
What are the 3 phases of Acute Renal Failure?
- induction
- maintenance
- recovery
What is Induction?
the time from the initial insult until decreased renal function is apparent (hours to days)
What is Maintenance?
the time period during which renal tubular damage occurs (weeks to months)
What is Recovery?
the time during which renal function improves, existing nephrons hypertrophy and compensate for those damaged and tubular repair occurs (when possible)
What are the causes of Acute Renal Failure?
- nephrotoxic drugs (aminoglycosides, chemotheraputic agents, antifungal meds, analgesics, anesthetics, toxins: antifreeze)
- infections(pyelonephritis)
- immune mediated diseases (glomerulonephritis)
- metabolic (hypercalcemia, addison’s)
What are C/S of Acute Renal Failure?
- kidneys are enlarged and painful on palpation
- signs of azotemia( anorexia, dehydrated, vomiting, diarrhea, weakness)
- fever
How do you diagnose Acute Renal Failure?
- urinalysis (urine sediment/casts, low sp. gravity)
- CBC (dehydration, increased PCV, acidosis)
- chem panel (increased BUN, creatinine, phosphorus, potassium
How do you treat Acute Renal Failure?
- relieve tubular obstruction
- discontinue toxic drugs
- iv fluids (start with normal saline)
- correct dehydration
- correct acid/base and electrolyte balance
What is Client Info for Acute Renal Failure?
- renal function may never return
- prognosis is guarded with older pets
- appropriate diet
- adequate water access
What is Chronic Renal Failure?
- common in older pets
- cats more than dogs
- irreversible and progressive decline in renal function
What is the Signalment for Chronic Renal Failure?
- dogs: older than 8
- cats: older than 10
What is the first function lost in Chronic Renal Failure?
ability to concentrate urine
What are other functions lost in Chronic Renal Failure?
- ability to cleanse blood
- azotemia starts at 75% nephron loss
What are C/S of Chronic Renal Failure?
- dull, lethargic, weak
- anorexia, wt. loss
- constipation
- PU/PD, cervical ventroflexion
- sudden blindness
How do you diagnose Chronic Renal Failure?
- acidosis
- anemia
- increased BUN, CREA
- hyperphosphatemia, hypokalemia
- proteinuria
How do you treat Chronic Renal Failure?
- fluids for dehydration
- potassium gluconate, calcium carbonate for electrolyte imbalances
- phosphorus binders
- sodium bicarbonate for pH adjustment
- hormones (epo)
- Vit. B supplements
What are causes of Urinary Incontience
- neurogenic: loss of normal neural function causing a paralyzed bladder
- ectopic uterus
- patent uracus
- endocrine imbalance (after spay)