Urinary System and Opthalmic Diseases Flashcards

1
Q

What are the functions of the Kidneys?

A
  • produce urine: excretion
  • maintain homeostasis: blood filtration, reabsorption, secretion; fluid balance regulation; acid-base balance regulation; hormone production
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2
Q

What is Feline Cystitis?

A

nonmalignant inflammatory condition that occurs frequently in cats

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3
Q

What is the cause of Feline Cystitis?

A
  • cause is unknown
  • multi factorial
  • not caused by bacteria
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4
Q

What is the Signalment of Feline Cystitis?

A
  • cats 2-6 yrs old

- occurs more in males than females

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5
Q

What are C/S of Feline Cystitis?

A
  • pollakuria
  • hematuria
  • dysuria
  • periuria (inappropriate urination)
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6
Q

How do you diagnose Feline Cystitis?

A
  • urinalysis/culture: to rule out bacteria as cause

- radiographs: to rule out calculi. contrast studies may show thickened bladder wall

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7
Q

How do you treat Feline Cystitis?

A
  • avoid unnecessary use of antibiotics
  • change diet to produce dilute urine
  • reduce stress from other cats, kids, etc: provide hiding places, pheromonotherapy
  • behavior modification drugs: amitrypitilline, clomipramine
  • glycosaminoglycan replacement: cosequin, adequan
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8
Q

What is Client Info for Feline Cystitis?

A
  • disease is self limiting: resolution of c/s in 7-10 days
  • may be reccuring problem
  • no definitive cure
  • reduce stress
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9
Q

What are the natural defense mechanisms of the Kidneys?

A
  • frequent voiding of urine
  • urethral and ureteral peristalsis
  • glycosaminoglycans in the surface mucosal layer
  • pH
  • constituents of urine
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10
Q

What is the cause of Canine Bacterial Cystitis?

A

ascending bacteria up the urethra

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11
Q

What are the C/S of Canine Bacterial Cystitis?

A
  • increased frequency of urination
  • hematuria
  • dysuria
  • cloudy urine, abnormal color
  • frequent licking of vaginal/urethral area
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12
Q

How do you diagnose Canine Bacterial Cystitis?

A
  • urinalysis: increased WBC’s and bacteria

- urine culture and sensitivity: collect by cytocentesis

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13
Q

How do you treat Canine Bacterial Cystitis?

A
  • antibiotics according to sensitivity: acute infections (10-14d), subsequent infections(4-6 weeks)
  • avoid trauma to urinary tract during surgery
  • indwelling catheters should be closed system
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14
Q

What is Client Info for Canine Bacterial Cystitis?

A
  • can resolve without treatment
  • give antibiotics as directed
  • prostate may be source of recurring infections
  • urine cultures should be repeated
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15
Q

What are the 2 most common types of urethral blockages?

A
  • uroliths

- urethral plugs

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16
Q

What are Uroliths?

A

composed of minerals and a small amount of matrix

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17
Q

What are Urethral Plugs?

A

composed of small amount of minerals and large amount of matrix

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18
Q

What are the 3 different types of struvites that occur in cats?

A
  • sterile urocystoliths
  • infection-induced urocystolith
  • matrix-struvite urethral plug
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19
Q

What are C/S of Feline Uroliths and Urethral Plugs?

A
  • hematuria
  • dysuria
  • periuria
  • anorexia, vomiting
  • collapse, death
  • non-specific signs: hiding, crying while urinating, frequent trips to litter box
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20
Q

How do you diagnose Feline Uroliths and Urethral Plugs?

A
  • palpation of bladder: full and tight
  • radiographs: double contrast study may be indicated
  • ultrasound:locate position of urolith
  • urolith analysis: necessary to determine type
  • EKG: atrial standstill, bradycardia, hyperkalemia
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21
Q

What is the Medical Treatment (chronic, non obstructed) of Feline Uroliths and Urethral Plugs?

A
  • dissolve struvite uroliths by acidifying urine and feeding diet low in Mg
  • cystotomy to remove stones
  • antibiotics according to culture/sensitivity
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22
Q

What is the Medical Treatment (obstructed) of Feline Uroliths and Urethral Plugs?

A
  • this is a medical emergency!
  • anesthetize (short acting)
  • pass tom cat catheter and back flush
  • sew catheter in place for 1-3 days, using closed system
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23
Q

What is the Medical Treatment (chronic obstructers) for Feline Uroliths and Urethral Plugs?

A
  • perineal urethrostomy

- goal of surgery is to decrease the likelihood of life-threatening obstruction

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24
Q

What are C/S of Canine Urolithiasis?

A
  • pollakiuria
  • dysuria
  • hematuria
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25
Q

How do you diagnose Canine Urolithiasis?

A
  • urinalysis (crystalluria, hematuria, increased bacteria)

- radiographs (double contrast study if necessary)

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26
Q

How do you treat Canine Urolithiasis?

A
  • change diet
  • acidify urine (urinary acidifiers)
  • increase urine output ( add salt to diet)
  • antibiotics for bacterial infection
  • surgical removal (calcium oxalate)
  • stone analysis is vital for appropriate treatment
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27
Q

What is Client Info for Canine Urolithiasis?

A
  • special diet may be required for life
  • table scraps/treats should be limited
  • long term antibiotics may be required
  • uroliths may recur at any time
  • always provide plenty of water
  • allow plenty of bathroom time and frequency
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28
Q

Renal Failure is due to what?

A
  • decreased blood flow

- damage to nephron and glomerular fitration declines resulting in azotemia

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29
Q

What are the 3 phases of Acute Renal Failure?

A
  • induction
  • maintenance
  • recovery
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30
Q

What is Induction?

A

the time from the initial insult until decreased renal function is apparent (hours to days)

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31
Q

What is Maintenance?

A

the time period during which renal tubular damage occurs (weeks to months)

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32
Q

What is Recovery?

A

the time during which renal function improves, existing nephrons hypertrophy and compensate for those damaged and tubular repair occurs (when possible)

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33
Q

What are the causes of Acute Renal Failure?

A
  • nephrotoxic drugs (aminoglycosides, chemotheraputic agents, antifungal meds, analgesics, anesthetics, toxins: antifreeze)
  • infections(pyelonephritis)
  • immune mediated diseases (glomerulonephritis)
  • metabolic (hypercalcemia, addison’s)
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34
Q

What are C/S of Acute Renal Failure?

A
  • kidneys are enlarged and painful on palpation
  • signs of azotemia( anorexia, dehydrated, vomiting, diarrhea, weakness)
  • fever
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35
Q

How do you diagnose Acute Renal Failure?

A
  • urinalysis (urine sediment/casts, low sp. gravity)
  • CBC (dehydration, increased PCV, acidosis)
  • chem panel (increased BUN, creatinine, phosphorus, potassium
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36
Q

How do you treat Acute Renal Failure?

A
  • relieve tubular obstruction
  • discontinue toxic drugs
  • iv fluids (start with normal saline)
  • correct dehydration
  • correct acid/base and electrolyte balance
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37
Q

What is Client Info for Acute Renal Failure?

A
  • renal function may never return
  • prognosis is guarded with older pets
  • appropriate diet
  • adequate water access
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38
Q

What is Chronic Renal Failure?

A
  • common in older pets
  • cats more than dogs
  • irreversible and progressive decline in renal function
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39
Q

What is the Signalment for Chronic Renal Failure?

A
  • dogs: older than 8

- cats: older than 10

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40
Q

What is the first function lost in Chronic Renal Failure?

A

ability to concentrate urine

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41
Q

What are other functions lost in Chronic Renal Failure?

A
  • ability to cleanse blood

- azotemia starts at 75% nephron loss

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42
Q

What are C/S of Chronic Renal Failure?

A
  • dull, lethargic, weak
  • anorexia, wt. loss
  • constipation
  • PU/PD, cervical ventroflexion
  • sudden blindness
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43
Q

How do you diagnose Chronic Renal Failure?

A
  • acidosis
  • anemia
  • increased BUN, CREA
  • hyperphosphatemia, hypokalemia
  • proteinuria
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44
Q

How do you treat Chronic Renal Failure?

A
  • fluids for dehydration
  • potassium gluconate, calcium carbonate for electrolyte imbalances
  • phosphorus binders
  • sodium bicarbonate for pH adjustment
  • hormones (epo)
  • Vit. B supplements
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45
Q

What are causes of Urinary Incontience

A
  • neurogenic: loss of normal neural function causing a paralyzed bladder
  • ectopic uterus
  • patent uracus
  • endocrine imbalance (after spay)
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46
Q

What are C/S of Urinary Incontience?

A
  • urine leakage while sleeping or exercising
  • perianal area of pet is always wet
  • concurrent UTI
47
Q

How do you diagnose Urinary Incontinence?

A
  • urinalysis
  • xrays, cystography
  • chem panel to r/o PU from endocrine disease
48
Q

How do you treat Urinary Incontinence?

A
  • surgical correction
  • diethylstillbestrol (endocrine)
  • phenylpropanolamine (loss of sphincter tone)
49
Q

What is the Conjunctiva?

A

pink tissue that lines the inner surface of the eyelids and covers the front portion of the eyeball except for the cornea

50
Q

What are causes of Conjunctivits?

A
  • allergy
  • anatomic (ectropion, entropion)
  • bacterial infection (injury, decreased tear production, foreign body, respiratory disease)
51
Q

What are causes of Conjunctivitis in cats?

A
  • feline herpes virus
  • calicivirus
  • chlamydia psittaci bacteria
  • mycoplasm
52
Q

What are C/S of Conjunctivitis?

A
  • redness
  • chemosis (swelling of conjunctiva)
  • ocular discharge (tears, mucus)
53
Q

How do you diagnose Conjunctivits?

A
  • rule out FB

- rule out dry eye: schirmer tear test

54
Q

How do you treat Conjunctivitis?

A

topical antibiotic ointment

55
Q

What is Client Info for Conjunctivitis?

A
  • don’t allow dogs to ride with head out window
  • keep medial canthus clean
  • vaccinate kittens
  • don’t touch eye with applicator
  • discard unused meds
56
Q

What is Epiphora?

A

excessive tearing

57
Q

What are causes of Epiphora?

A
  • overproduction of tears (ocular pain, irritation)

- faulty drainage by lacrimal system (blockage of duct, puncta, imperforate puncta, trauma)

58
Q

What are C/S of Epiphora?

A
  • watering of eye

- discoloration of hair

59
Q

How do you diagnose Epiphora?

A

fluorescein dye test

60
Q

How do you treat Epiphora?

A
  • treat initial cause
  • flush lacrimal duct
  • surgically open imperforate puncta
  • topical antibiotic ointment
  • keep hair trimmed around eyes
61
Q

What is Entropion?

A

eyelids that roll in against the cornea

62
Q

What are causes of Entropion?

A
  • congenital (large orbits w/deep set eyes, collies, great danes)
  • poor ocular muscle development
  • trauma
  • secondary to painful corneal lesion, conjunctiva inflammation
63
Q

What are C/S of Entropion?

A
  • epiphora
  • chemosis
  • conjunctivitis
  • pain
  • corneal ulceration
  • photophobia
64
Q

How do you treat Entropion?

A
  • surgical is TOC
  • temp. mattress suture to evert eye (young animals)
  • lateral canthoplasty
  • hotz-celsus (remove elliptical piece of tissue from under eye)
65
Q

What are causes of Ectropion?

A
  • congenital

- bassets, bloodhounds, cocker spaniel, st. bernard

66
Q

What are C/S of Ectropion?

A
  • conjunctivitis
  • ephiphora
  • keratitis
  • purulent discharge
67
Q

How do you treat Ectropion?

A
  • surgery to shorten eye lid

- other procedures

68
Q

What causes Cherry Eye?

A

unknown

69
Q

What is the Signalment for Cherry Eye?

A

bassets, beagle, boston terrier, cocker spaniel

70
Q

What are C/S of Cherry Eye?

A
  • young dogs (less than 2)
  • epiphora
  • usually no pain
71
Q

How do you diagnose Cherry Eye?

A

to r/o tumor

72
Q

How do you treat Cherry Eye?

A
  • surgery to remove gland, not recommended

- suture back in place

73
Q

What is Glaucoma?

A

increased intraocular pressure

74
Q

What are causes of Glaucoma?

A
  • inherited (c. spaniel, basset, chow)

- secondary(neoplasia, luxation of lens, hemorrhage, uvetitis)

75
Q

What are C/S of Glaucoma?

A
  • ocular pain
  • episcleral injection
  • corneal edema
  • dilated pupil
  • blind
76
Q

How do you diagnose Glaucoma?

A

IOP >30mm Hg

77
Q

How do you treat Acute Glaucoma?

A
  • latanoprost
  • dichlorphenamide
  • surgical (cryosurgery or laser)
78
Q

How do you treat Chronic Glaucoma?

A

enucleation to remove pain

79
Q

What are the causes of Ulcerative Keratitis?

A
  • trauma
  • chemical burns
  • foreign objects
  • KCS (keratoconjunctivitis sicca)
  • conformation abnormalities
  • herpes virus (cats)
80
Q

What are C/S of Ulcerative Keratitis?

A
  • pain
  • epiphora
  • blepharospasm
  • hyperemia of conjunctiva
81
Q

How do you diagnose Ulcerative Keratitis?

A

fluorescein dye to cornea

82
Q

How do you treat Ulcerative Keratitis?

A
  • topical atropine ointment
  • topical broad spectrum antibiotic ointment
  • viral ointments or solutions
  • surgery (eye lid flap, conjunctival flap)
  • serum (autologous)
83
Q

What is Desmetocele?

A

erosion to membrane

84
Q

What is Client Info for Ulcerative Keratitis?

A
  • most heal without treatment
  • avoid using old meds
  • cortisone will inhibit healing of ulcer
  • don’t touch eye with applicator tip
85
Q

What is Pannus?

A

superficial corneal vascularzation/scar tissue

86
Q

What is the cause of Chronic Superficial Keratitis (Pannus)

A
  • thought to be immune mediated (infiltration of cornea with lymphocytes, plasma cells)
  • increased UV light/high altitudes increases incidience
87
Q

What are C/S of Chronic Superficial Keratitis?

A

opaque lesions that begin at limbus and extend into cornea (milky, pink or tan)

88
Q

What breeds are affected by Chronic Superficial Keratitis?

A
  • german shepherds
  • border collies
  • greyhounds
  • siberian husky
89
Q

How do you diagnose Chronic Superficial Keratitis?

A
  • to r/o KCS, corneal ulcers

- corneal scrapings

90
Q

How do you treat Chronic Superficial Keratitis?

A
  • corticosteroids when lifelong
  • cyclosporine often lifelong
  • antibiotic eye ointment
91
Q

What is Client Info for Chronic Superficial Keratitis?

A

-no cure
-if Rx is stopped, disease will return and progress
high altitudes and increased sun predispose animals

92
Q

What is the cause of KCS?

A

-lack of tear production

93
Q

What are C/S of KCS?

A
  • recurrent conjunctivitis, corneal ulcers, keratitis
  • dull, dry, irregular cornea, conjunctiva
  • tenacious, mucoid ocular discharge
  • blepharospasm
  • crusty nares
94
Q

How do you diagnose KCS?

A

schirmer tear test

95
Q

How do you treat KCS?

A
  • tear stimulation (cyclosporine, pilocarpine)

- arttificial tears

96
Q

What are causes of Cataracts?

A
  • genetic
  • secondary to:
  • diabetes mellitus
  • trauma
  • lens luxation
  • nutritional deficency
  • uveitis
  • hypocalcemia
  • electrical shock
97
Q

How do you treat Cataracts?

A
  • surgical removal of lens

- treat underlying cause

98
Q

What are C/S of Cataracts?

A
  • progressive loss of vision

- opaque pupillary opening

99
Q

How do you diagnose Cataracts?

A

opthalmascope

100
Q

What is Progressive Retinal Atropy?

A

group of hereditary disorders causing loss of rods, cones and/or blood supply

101
Q

What breeds are effected by PRA?

A
toy/minature poodle
golden retriever
irish setter
cocker spaniel 
schnauzer
collie
samoay
nor. elkhound
102
Q

What are C/S of PRA?

A
  • slow onset of blindness
  • night vision goes first due to lack of rods
  • loss of day vision (cones)
103
Q

How do you diagnose PRA?

A

eye exam (gray, granular app. of retina, hyperreflective lens, muscular attenuation, optic nerve atropy)

104
Q

How do you treat PRA?

A

none

105
Q

What is Client Info for PRA?

A

inherited disease
blind animals adapt well
cats need balanced diet

106
Q

What is Anterior Uveitits?

A

inflammation of uvea (ciliary body, iris, choroid)

107
Q

What are causes of Anterior Uveitis?

A
  • inflammation/infection
  • neoplasia
  • trauma
108
Q

What are C/S of Uveitis?

A
  • blepharospasm
  • aqueous flare
  • miosis of affected eye
  • iridal swelling or congestion
  • keratic precipitates
  • ciliary flush in limbal region
  • corneal edema
  • hyphema
109
Q

How do you treat Uveitis?

A
topical steroids
topical anti inflammatory drugs
systemic steroids
atropine
antibiotics
110
Q

What are causes of Proptosed Globes?

A
  • trauma
  • conformation
  • retrobulbar abscess or neoplasia
111
Q

What are reasons you would save the eye in a Proptosed Globe?

A
  • brachycephalic breed
  • positive direct or consensual pupillary light response
  • normal findings on posterior segment exam
  • proptosed eye with vision on initial presentation
112
Q

What are reasons you would remove the eye in Proptosed Globe?

A
  • non brachycephalic breed
  • cat breed
  • hyphema
  • no visible pupil
  • facial fractures
  • optic nerve damage and avulsion of 3 or more extraocular muscles
113
Q

How do you treat a Proptosed Globe?

A
lubricate immediately
reduce the globe into the socket ASAP 
enucleation if optic nerve is severed
systemic and topical antibiotics
steroids