URINARY SYSTEM Flashcards
Organs of the Urinary system
• Kidneys
• Ureters
• Urinary bladder
• Urethra
Functions of the Urinary System
• Elimination of waste products (nitrogenous waste, toxins and drugs)
• Regulate aspects of
homeostasis (water balance, electrolytes, acid-based balance, blood pressure, RBC production and activation of vit. D)
• Retroperitoneal bean-shaped organ in superior lumbar region
• Extends from vertebral levels T12 superiorly and L3 inferiorly
• Coverings: (from innermost to outermost)
• Renal capsule
• Perirenal fat
• Renal fascia
kidneys
Regions of the kidney
renal cortex, medulla, and pelvis
outer region
renal cortex
inside the cortex
renal medulla
inner collecting tube
Renal pelvis
Kidney Structures
Medullary pyramids, Renal columns and calyces
triangular regions of tissue in the medulla
Medullary pyramids
extensions of cortex-like
material inward
Renal columns
cup-shaped structures that funnel
urine towards the renal pelvis
calyces
• Functional units of kidney
• 1-1.5 million
nephron
2 types of nephron
Cortical and Juxtamedullary
➢Removal of waste and reabsorption of
nutrients
cortical (85%)
Concentration
of urine
Juxtamedullary
Parts of Nephron
Glomerulus
Renal Tubule
a high-pressure tuft of capillaries with openings
• Attached to
arterioles on both sides
• Large afferent arteriole
• Narrow efferent arteriole
Glomerulus
• Bowman’s capsule
• Proximal Convoluted Tubule (PCT)
• Loop of Henle
• Distal Convoluted Tubule (DCT)
Renal Tubule
Layers of Bowman’s capsule
Outer parietal layer and Inner visceral layer
composed of simple
squamous epithelium
Outer parietal layer
composed of branching
podocytes which cling to the glomerulus
Inner visceral layer
• Arise from efferent arteriole of the glomerulus
• Cling close to the renal tubule
• Reabsorb some substances from collecting tubes
Peritubular Capillaries
glomerulus plus the Bowman’s
capsule
Renal / Malphigian Corpuscles
consists of juxtaglomerular cells of the
afferent arteriole and the macula densa of the DCT
Juxtaglomerular apparatus
Mechanism of Urine Formation
- Glomerular filtration
- Tubular reabsorption
- Tubular secretion
• Involves passing the blood through layers of filtration barrier which
includes:
• Glomerular endothelial cell
• Basement membrane
• Epithelial cells of Bowman’s capsule
• Nonselective passive process
• Filtrate is collected in the glomerular capsule and leaves via the
renal tubule
Glomerular Filtration
Factors Affecting Filtration Process
- Cellular structure of the capillaries and the
Bowman’s capsule - Glomerular Pressure
- Renin-angiotensin-aldosterone system
3 types of Glomerular Filtration
Glomerular hydrostatic pressure
Glomerular osmotic pressure
Capsular hydrostatic pressure
Chief force pushing water and solute across the filtration membrane
Glomerular hydrostatic pressure