Upper GI Flashcards
What are the different types of vomiting?
Vomiting with retching
Projectile vomiting
Bilious vomiting
Effortless vomiting
Haematemesis
What symptoms are seen in the pre-ejection phase of vomiting?
Pallor
Nausea
Tachycardia
Upon a blood gas, what would be seen in a patient with pyloric stensosi?
Metabolic alkalosis
If you suspect pyloric stenosis, what should be done?
Refer to surgeons, they will carry out Ramstedt’s pyloromyotomy
In which age group does pyloric stenosis occur in?
Babies 4-12wks
What type of vomiting is seen in pyloric stenosis?
Projectile non-bilious vomiting
What symptoms are seen in pyloric stenosis?
Projectile non-bilious vomiting
Weight loss
Dehydration +/- shock
What is the characteristic electrolyte disturbance seen in pyloric stenosis?
Metabolic alkalosis
Hypochloraemia
Hypokalaemia
Bilious vomiting should always ring alarm bells.
What is bilious vomiting until proved otherwise?
Intestinal obstruction
What are some of the causes of intestinal obstruction, and therefore bilious vomiting?
Intestinal atresia
Malrotation
Intussusception
Crohns disease with structures
Investigations for bilious vomiting to rule out intestinal obstruction?
Abdominal x-ray
Consider contrast meal
Surgical opinion e.g. exploratory laparotomy
What is effortless vomiting almost always caused by?
Gastro-oesophageal reflux
What is the treatment for gastro-oesophageal reflux and effortless vomiting?
Resolves on its own in most cases
What are the situations where gastro-oesophageal reflux will not resolve by itself?
Cerebral palsy
Progressive neurological problems
Oesophageal atresia
Generalised GI motility problem
How long after birth does gastro-oesophageal reflux tend to occur?
2 weeks after birth
->can get worse for four to six months
Investigations for gastro-oesophageal reflux?
History and examination usually sufficient
Can do barium swallow, pH studies. oesophageal impedance monitoring, endoscopy
What is done in terms of feeding for infants with gastro-oesophageal reflux?
Thickeners for liquids
Feeding position- propped up after feeds
->bigger teat in bottle required
What is done in terms of nutrional support for infants with gastro-oesophageal reflux?
Calorie supplements
Exclusion diet- milk
NG tube
Gastrotomy
Medical treatment of GORD?
Feed thickener
Prokinetic drugs
Acid suppressing drugs e.g. PPI
What are some of the indications for surgery in GORD?
Failure of medical treatment
Persistent failure to thrive, aspiration, oesophagitis
What colour will the vomit be if it is bilious?
Green
->not yellow. Green.
What is meant by chronic diarrhoea?
4 or more stools per day for 4wks
What is meant by osmotic diarrhoea?
Movement of water into the bowel to equilibrate osmotic gradient
->usually a feature of malabsorption
What is osmotic diarrhoea generally accompanied by?
Macroscopic and microscopic intestinal injury
What is secretory diarrhoea associated with?
Toxin production from Virbio cholerae and E.Coli
Which type of diarrhoea is always pathological?
Nocturnal diarrhoea
If there is fat malabsorption, and fat is appearing in stools, what may be the cause?
Hepatobiliary disease-chronic liver disease, cholestasis
Pancreatic disease-diarrhoea due to lack of lipase, cystic fibrosis
Which genes mean there is genetic susceptibility to coeliac disease?
HLA DQ2, DQ4
Symptoms of coeliac disease in children?
Bloating
Diarrhoea
Failure to thrive
Short stature
Constipation
Tiredness
Dermatitis herpatiformis
Okay to check you were paying attention…
Which skin change can be observed in coeliac disease?
Dermatitis herpatiformis
If a child has coeliac disease, which condition are they screened for every two years?
Type 1 diabetes
Gold standard investigation to diagnose coeliac disease?
Duodenal biopsy
->but not done in everyone, if the anti TTG is more than ten times the upper limit of normal and the anti-endomysial is positive, diagnosis is made without the biopsy
Which other tests are useful in the diagnosis of coeliac disease?
Anti-tissue transglutaminase
Serum IgA
Anti-endomysial
Genetic testing for HLA DQ2, DQ4
Histological findings of coeliac disease?
Villous atrophy
Crypt hyperplasia
Treatment of coeliac disease?
Gluten free diet for life