Dermatology Flashcards

1
Q

What is eczema?

A

Red, dry, itchy skin eruption

Common, affects 1 in 5 children

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2
Q

Atopic eczema is thought to be a barrier defect. What does this mean?

A

There is increased permeability to irritants and allergens, which explains why it is itchy.

There is also water loss, which explains why it is dry.

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3
Q

Give an example of a mild topical steroid.

A

Hydrocortisone

->widely used

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4
Q

Give an example of a moderate topical steroid.

A

Eumovate

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5
Q

Give an example of a potent topical steroid.

A

Betnovate

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6
Q

Give an example of a very potent topical steroid.

A

Dermovate

->rarely used in children

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7
Q

Okay summarise the topical steroid ladder.

A

Very potent- Dermaovate
Potent- Betnovate
Moderate- Eumovate
Mild- Hydrocortisone

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8
Q

How long should you use mild-moderate steroids on the face?

A

3-5 days, then stop and repeat as needed

->using more than required can cause skin thinning in prolonged use

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9
Q

If topical steroids don’t help atopic eczema, what should be considered?

A

Think about triggers, may be a more allergy based response, hence why steroids aren’t helping

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10
Q

Alternatives for topical steroids in atopic eczema?

A

Steroid sparing agents- protopic ointment or Elidel cream
Phototherapy UVB
Immunosuppression- methotrexate, ciclosporin
Biologics- dupilomab

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11
Q

If eczema has started at a very young age, what may be the trigger?

A

Milk

->often GI side effects too and failure to thrive

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12
Q

What type of hypersensitivity reaction is eczema?

A

Either type I or IV

Type I- immediate reactions

Type IV- prolonged reactions

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13
Q

What is seen in discoid eczema?

A

Scattered circular patches of itchy eczema.
Stubborn to treat.

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14
Q

I just mentioned that discoid eczema is stubborn to treat, but what can be done?

A

Requires potent topical steroid, often in combination with an antibacterial component.

e.g. Betnovate C ointment

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15
Q

Where on the body is seborrheic dermatitis usually seen?

A

Face and scalp

->associated with cradle cap in infants

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16
Q

What age is seborrheic dermatitis associated with in children?

A

<3mths, usually resolves by 12mths

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17
Q

Treatments of seborrheic dermatitis?

A

Emollients- to loose scale
Daktocort ointment
Protopic ointment

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18
Q

Causative microorganisms of impetigo?

A

Staph.aureus

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19
Q

Appearance of impetigo?

A

Golden crust and pustules

Very infectious

20
Q

Treatment for impetigo?

A

Topical antibacterial e.g. fucidin
Oral antibiotic e.g. flucloxacillin if not improving with topical

21
Q

What is seen in molluscum contagiosum?

A

Pearly papules, umbilicated centre

22
Q

What causes molluscum contagiosum?

A

Molluscipox virus

23
Q

Is molluscum contagiosum contagious?

A

Yes, transmission to close direct contacts

24
Q

Treatment of molluscum contagiosum?

A

Reassurance, self-limiting

Can take 24 mths to clear

->if parents very concerned, can use 5% Potassium Hydroxide as this causes inflammation and turns body’s immune system towards the virus

25
Can viral warts be transmitted?
Yes, by direct skin contact
26
Which virus tends to cause viral warts?
HPV
27
Treatment of viral warts?
No treatment required, stimulate own immune response to them ->if worried, topical treatments such as salicylic acid and paring
28
What causes erythema infectiosum (aka slapped cheek disease)?
Parvovirus B19
29
Which virus causes chickpox?
Varicella zoster
30
What is seen in chickenpox?
Red papules progressing to vesicles (blisters), often starting on the trunk Itchy Associated with viral symptoms
31
What is seen in slapped cheek disease/erythema infectiosom?
Erythematous rash, cheeks initially and then lace like rash on trunk and limbs
32
Treatment of slapped cheek disease/erythema infectiosum?
Usually self-limiting, can take up to 6wks to disappear
33
What can slapped cheek disease result in?
Very rarely, but aplastic crisis ->if patient has haemolytic disorders
34
What can happen in a pregnant woman in infected by erythema infectiosum?
Spontaneous abortion Intrauterine death Hydrops fetalis
35
What is the usual cause of hand, foot and mouth disease?
Enterovirus caused, usually Coxsackie virus A16
36
What is seen in hand, foot and mouth disease?
Blisters on the hands, feet and in the mouth Viral symptoms
37
Treatment of hand, food and mouth disease?
Self limiting Supportive treatment
38
What is the difference is presentation between a child with eczema coxsackium and eczema herpeticum?
Eczema coxsackium- history of eczema, self limitng. Eczema herpeticum- history of eczema, child more unwell and requiring treatment.
39
What is the treatment fir eczema herpetcium?
Withhold steroids for 24hrs Aciclovir- oral or IV ->ophthalmology review if near eye Stop steroids as continuing can make rash spread further
40
What is erythema nodosum associated with?
IBD Sarcoidosis Infections- streptococcus, URTI
41
Treatment of erythema nosodum?
Treat underlying causes NSAIDs
42
What is dermatitis herpetiformis associated with?
Coeliac disease
43
How long is urticaria present for to be classed as chronic urticaria?
>6wks
44
Treatment of urticaria?
Antihistamines Avoid trigger
45
What is meant by infantile haemangioma?
Very common vascular birth mark Not present on skin at birth but there is a proliferative phase between 6wks and 8mths
46
Treatment of infantile haemangioma?
Reassurance ->beta blockers can speed up process of involution
47