Unit 7: Physical Health Flashcards
What is LIFE EXPECTANCY, and how have these changed over the last 100 years?
the length of time a person is expected to live
1900 = 46.3 for men, 48.3 for women
2016 = 76.1 for men, 81.1 for women
What are MORTALITY and MORBIDITY?
Mortality = death
Morbidity = illness
What is the primary reason for the significant increase in life expectancies over the last 100 years?
longevity has increased with the development of vaccines and treatments for common diseases; refrigeration; insect control
however, “diseases of old age” have now replaced infectious diseases among the top causes of death (heart disease, cancer, Alzheimers)
What are the current sex statistics regarding causes of death?
Men = for every one of the top causes of death, except Alzheimers, men die at higher rates; suffer life threatening conditions more often than women
Women = tend to suffer from chronic, nonfatal, debilitating conditions more often than men (arthritis, osteoporosis, autoimmune)
What is the MORTALITY-MORBIDITY PARADOX?
a phenomenon in which women tend to have higher rates of morbidity (sickness) than men, but men tend to experience mortality (death) earlier than women
What is one of the proposed reasons that women self-report poorer health?
the traditional role of women as caretaker contributes to their poorer health bc being a caretaker can increase stress and make people vulnerable to various debilitating conditions
What is one of the proposed reasons that females, in both human and non-human species, have a longer lifespan?
Having 2 X chromosomes may be a health advantage > sex chromosomes sometimes carry genetic mutations that code for diseases > most sex-linked diseases are passed down through the X chromosome (more genes than the Y) > among people with 2 X chromosomes, if they carry an abnormal, disease producing gene on one X chromosome, the normal gene on the other can override the abnormal gene and prevent expression of the disease
THUS: men are more vulnerable to X-linked diseases than women
What is a TELOMERE and how are these related to lifespan?
TELOMERE: disposable DNA sequences at the end of chromosome strands that protect the remaining genes on the chromosomes during cell-division
telomeres get shorter each time a cell divides, until eventually the cell dies when it can no longer divide
telomeres of men and women are the same length at birth, male telomeres seem to shorten faster than women’s, suggesting their cells age faster
Describe testosterone influences on longevity.
high doses of experimentally administered testosterone decreased “good” cholesterol (HDL) and increased “bad” cholesterol (LDL), increasing risk of cardiovascular disease
testosterone suppresses the immune system, which can help explain why women have more robust immune systems
Describe estrogen influences on longevity.
women who have high levels of estrogen (premenopausal) have less cardiovascular disease and lower blood pressure than age-matched men
estrogen increases cardiac output during the menstrual cycle, mimicking the effect of exercise
increases the expression of longevity associated genes
can increase risk of certain forms of cancer (breast, uterine, ovarian)
How has evolution potentially affected longevity in men?
men evolved to pursue a “live hard, die young” strategy bc this results in more offspring, even if it means earlier average age of death
men’s higher concentration of testosterone may reflect evolutionary pressures on men to compete aggressively for mates, but increases vulnerability to infection
testosterone is good for reproduction, bad for long-term health and survival
How has evolution potentially affected longevity in women?
women’s bodies contribute more directly to healthy fetal growth and infant nourishment, evolved to invest more energy into fighting disease and repairing damaged cells > slows the aging process
^ may reflect an adaptation to evolutionary pressures on women to gestate and bear healthy, viable children
What was the most prevalent link to leading causes of death in 2015, and what is relevant about this regarding sex differences?
to some extent, an individuals behaviours (diet, exercise, alcohol, smoking, drug use)
the more behaviour contributes to a given cause of death, the larger the sex difference in rates of death from that cause
Describe the relevance of risky behaviour in men’s health and longevity.
accidental deaths are the 4th leading cause of death for men in the US (7th for women)
workplace injuries, risky tasks at home, more accident-prone leisure activities, more likely to own a gun, more likely to drive recklessly
How is HIV related to men’s health and longevity?
in the US, 81% of annual new cases of HIV occur among men (though globally, women account for about half of all cases)
among men, most cases of transmission occur during same-sex activity (However trans women are included in this group)
What is a RISK NETWORK?
extended networks of individuals with whom people have sexual contact or engage in other risky practices (IV drug use) that can transmit disease
What are HIGHLY ACTIVE ANTIRETROVIRAL THERAPIES (HAARTs)?
drug treatments, usually consisting of a combination of at least 3 drugs, that suppress HIV replication
not everyone in the world can afford or access these
have an ironic consequence of increasing people’s risky sex tendencies
What are the effects of smoking on men’s longevity?
5x as many men as women smoke globally
8.5x as many men are “hardcore smokers”
smoking is declining globally, as are the sex differences
women have a harder time quitting smoking > more likely to be using it to control weight