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Pathology Unit 5 Condensed > Unit 5 Tumor Markers > Flashcards

Unit 5 Tumor Markers Flashcards

1
Q

CEA

A

epithelial ovarian cancer

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2
Q

CA-125

A

use to monitor the progression of ovarian neoplasms

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3
Q

Estrogen

A

Leydig cell tumor
Thecoma
granulosa cell tumor

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4
Q

AFP

A

yolk sac tumor, teratoma

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5
Q

HCG

A

choriocarcinoma, hydatidiform mole (more in complete), teratoma, embryonal carcinoma

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6
Q

schistosomiasis with bladder lesion

A

squamous cell carcinoma of bladder

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7
Q

Benign testicular tumor in 4-12 y.o.

A

teratoma

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8
Q

placental alkaline phosphatase

A

seminoma and testicular carcinoma in situ

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9
Q

schiller duval bodies

A

yolk sac tumor

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10
Q

placetal ALP

A

seminoma

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11
Q

PAP + PSA +/- ALP

A

prostatic adenocarcinoma

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12
Q

Reinke Crystals

A

Leydig cell tumor

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13
Q

Androblastoma

A

Sertoli cell tumor

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14
Q

WT1 or WT2

A

Chromosome 11, Wilms Tumor

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15
Q

MEN2A or 2B + VHL, urinary VML

A

pheochromocytoma

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16
Q

Homovanillic acid (HVA), bombesin, N-myc

A

neuroblastoma

17
Q

RET, BRAF mutations

A

papillary carcinoma of thyroid

18
Q

calcitonin, MEN2A, RET

A

medullary carcinoma of thyroid

19
Q

Gastrin secreting and MEN1 assoc.

A

Zollinger-Ellison Syndrome

20
Q

MEN1

A

Parathyroid tumors, pituitary tumors, pancreatic endocrine tumors (zollinger-ellison, VIPoma, glucagonoma)

21
Q

MEN2A

A

medullary thyroid carcinoma, pheochromocytoma, parathyroid hyperplasia

22
Q

MEN2B

A

medullary thyroid carcinoma, pheochromocytoma, oral/intestinal ganglioneuromatosis, marfanoid habitus

23
Q

Call Exner bodies + estrogen/progesterone

A

Granulosa Cell tumor

24
Q

HCG + LDH

A

Dysgerminoma

25
Q

mucin-secreting signet cells

A

Krukenberg tumor

26
Q

desmin and spindle-shaped cells

A

rhabdomyosarcoma

Pathology Unit 5 Condensed (7 decks)

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