Unit 5: Notes 2 Flashcards

1
Q

what speeds up an action potential

A

Myelin and diameter

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2
Q

what is the condition of a nerve cell at resting potential (charge, location of different ions)?

A

-70, inside K+, outside Na+.

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3
Q

which Japanese delicacy is risky? and why?

A

The puffer fish. It contains tetrodotoxin, A substance that makes them and foul tasting and often lethal to fish

to humans, TTX is deadly, up to 200 times more poisonous than cyanide

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4
Q

what is an action potential

A

-how neurons communicate
-nerve impulse
-self propagating (following rules of dominoes)
-A large change in the membrane potential (difference in electrical charge)
> from - to +, back to -
> result from movement of Na+ and K+ through membrane channels

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5
Q

what are the types of channels in the axon?

A

leakage channels and gated channels

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6
Q

what are leakage channels

A

they allow small steady streams of ions to leak across the membrane

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7
Q

what are gated channels

A

Open and close on command

> voltage gated channels open in response to a change in membrane potential

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8
Q

resting neuron

A

resting neurons have a charge of -70 mV compared to outside

> A positive charge on the outside, negative charge on the inside

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9
Q

what is happening inside the neuron at rest

A

higher concentration of K+, so it leaks out fast

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10
Q

what is happening outside of the neuron at rest

A

higher concentration of Na+, so it leaks in slowly

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11
Q

what is the sodium potassium pump

A
  • The small Na+ inward leak and larger K+ outward leak is offset by the Na+/K+ pump
  • maintains resting membrane potential
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12
Q

name the steps of an action potential

A

depolarization, peak, repolarization, hyperpolarization

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13
Q

depolarization

A
  • stimulus causes voltage gated Na+ channels to open and Na+ rushes into the cell
  • cell becomes more positive
  • threshold = minimum level of stimulus (-55)
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14
Q

Peak

A
  • K+ channels begin to open and K+ begins to leave cell

- Na+ channels begin to close

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15
Q

Repolarization

A
  • K+ voltage gates fully open, K+ leaving cell
  • all Na+ Gates are closed
  • cells becoming more negative
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16
Q

Hyperpolarization

A
  • K+ Gates slowly close so cell becomes more negative than the resting value (-70)
  • leaking restores -70
17
Q

absolutely refractory period

A

Second action potential absolutely cannot occur

18
Q

relative refractory period

A

Second action potential difficult but not impossible