Unit 5 Flashcards

1
Q

motility

A

propulsive movements
* push contents forward

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2
Q

secretion

A

from exocrine glands into the GI tract

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3
Q

digestion

A

carbohydrates, protein, fat
* breakdown parts that can be absorbed

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4
Q

what happens when longitudinal muscle contracts

A

GI tract shortens

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5
Q

what happens when circular muscle contracts

A

decrease radius of GI tract

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6
Q

what does the symp (NE, Ep) do to the GI tract

A

relaxtion (inhibit)

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7
Q

what does the parasymp (ACh) do to the GI tract

A

contraction (stimulate)

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8
Q

what does the enteric system do to the GI tract

A

relaxtion AND contraction

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9
Q

gastrin source

A

stomach
* from stomach into the blood

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10
Q

gastrin simulus for release

A

protein (amino acids) in the stomach

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11
Q

gastrin function

A

stimulates gastric motility and secretions (HCl)

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12
Q

gastrin summary of function

A

stimulate stomach to digest food and clear out space in the instestines

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13
Q

secretin source

A

duodenum

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14
Q

secretin stimulus for release

A

acid in teh deuodenum

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15
Q

secretin function

A

inhibit gastric moltility and secretion
stimulate HCO3- secretion from pancrease and liver

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16
Q

secretin summary of function

A

too much acid coming into the small instestine

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17
Q

cholecystokinin (CKK) source

A

duodenum

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18
Q

cholecystokinin stimulus for release

A

fat or protein in the deuodenum

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19
Q

choleycystokinin function

A

inihbit gastric motility and sectrion
stimulate secretion of digestive enzymes from pancreas
contract gallbladder - release of bile salts into the duodenum

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20
Q

GIP source

A

duodenum

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21
Q

GIP stimulus for release

A

glucose inthe duodenum

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22
Q

GIP function

A

inhibit gastric motility and sectretion
stimulate insulin release

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23
Q

GIP summary of function

A

slow down rate of glucose in the duodenum and prepare for glucose in the blood

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24
Q

cholecystokinin summary of funciton

A

sow down rate of stuff enterig the duodenum and release enzymes to break it down

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25
GI smooth muscle contains
gap junction (single unit) pacemaker cells
26
peristalsis
propulsive movement in esophagus and intestines
27
segmentation
mixing movements in intestines
28
voluntary sphincter type of muscle
skeletal muscle
29
involuntary sphincter type of mucsle
smooth muscle
30
zymogen granules
contain amylase breakdown carbohydrates
31
duct cells
add bicarbonate (neutralize acidic foods)
32
salivary amylase
begins breakdown of carbohydrates (inactivated by low pH in stomach)
33
lingual lipase
begins breakdown of lipids works at low pH
34
what does the parasymp do to inhibit the stomach
stimulate enertic NS which inhibits the stomach to relax and expand
35
oxyntic gland
pit in the epithelium of the stomach with a large number of exocrine cells
36
parietal cells
release HCl and intrinsic factor
37
chief cells
have zymogen granules * release pepsinogen (protein breakdown)
38
cephalic phase
before food reaches the stomach * increase in gastric secretion - HCl, pepsinogen
39
gastric phase
food in the stomach - protein, stretch * increase in gastric sectrions
40
intestinal phase
food in the duodenum * decrease in gastric secretions
41
bactericidal action
low pH kills most bacteria (except H. poylori)
42
supply of intrinstic factor (parietal cells)
intrinsic facotr needed for Vit B12 absorption * Vit B12 needeed for RBC production
43
what is bile made of
HCO3- Bilirubin (gives feces brown color) Bile salts (emulsification of fat)
44
glucose can either
stay in blood or be stored as glycogen
45
amino acid function once reaching the liver
* stay in blood * converted into other amino acids * convert into glucose * plasma proteins
46
compositon of pancreatic juice
* HCO3- * proteases * pancreatic amylase * pancreatic lipase
47
pancreatic amylase
breakdown carbohydrates
48
pancreatic lipase
breakdown fat
49
small instestine absorptive state
segmantation and peristalsis
50
small intestine postabsorptive state
migrating motor complex
51
small intestine secretions
HCO3- bacteria cholera toxin (increase secretions)
52
main type of disaccharide
sucrose
53
main monosaccharide
glucose (only type that can be absorbed)
54
epithelial disaccharidase
disaccharides --> monosaccharides
55
how does glucose get into enterocytes
secondary active transport
56
how does glucose go from enterocytes to the blood
facilitated diffusion
57
most important lipase
pancreatic lipase * acting with bile salts present in duodenum
58
how does the micelle get into the enterocyte
simple diffusion
59
what part of the micelle does not go into the enterocyte
bile salts * absorbed in ileum and sent to liver to be reused
60
where does the chylomicron go after leaving the eneterocyte
lymphatic system
61
why types of peptides can be absorbed
tripeptides dipeptides amino acids
62
what pancreatic enzyme can do autocatalysis
trypsin
63
what panreatic enzyme is released by epithelial cells in duodenum and turns trypsinogen into trypsin
enteropeptidase
64
exopeptidase
remove amino acid from the end
65
endopeptidase
cleave polypeptide in the middle
66
what happens if proteins are absorbed
anaphylactic reaction (Antibody production --> vasodilation --> increase BP)
67
ferritin
storage form of iron
68
how does iron enter the enterocyte
primary active transport
69
ferroportin transporter
transports iron into the blood
70
hepsidin
inhibits ferroportin (decrease of iron absorption)