Unit 4: Pulmonary Pharmacology Flashcards
Drug classification:
Theo-dur
Methylxanthines
Drug classification:
Phentolamine
Sympatholytics
Side Effects for:
Sympathomimetics (selective)
- Nervoursness
- Headache
- Tremors
Side effects:
Leukotrienes
- None
- Often used in children
Drug classification:
phylline
Methylxanthines
Side effects:
Corticosteroids
- Osteoporosis
- Muscle wasting
- Skin breakdown
- Hyperglycemia
- Cataracts
Drug classification:
tropium
Parasympatholytics
Side effects:
Methylxanthines
- Can be life threatening!
- Therapeutic and toxics levels very close
- Plasma level monitored closely
Side effects:
Cromolyn and Nedocromil
- Typically not severe
- Irritation of nasal and upper respiratory passages
Drug classification:
erol
Sympathomimetics
(selective)
Drug classification:
sone
Corticosteroids
What input controls bronchodilation?
- SNS Beta2 Input
Drug classification:
leu
lukast
Leukotriene
leu = Synthesis Inhibitor
lukast = receptor antagonist
Drug classification:
Ephedrine
Epinephrine or adrenaline
Isoproterenol
Ethylnorepinephrine
Sympathomimetics (Non Selective)
Drug classification:
N-acetylcysteine
Mucolytic
What drug classification:
enol
Sympathomimetics
(selective)
What do the alpha and beta receptors affect?
- Beta1: Heart
- Beta2: Lungs
- Alpha1: Blood Vessels
- Alpha2: Organs
Side Effects for:
Sympathomimetics (non selective)
- Same as selective: nervousness, headache, tremors
- Beta stimulation: tachycardia, angina, cardiac dysrhythmias
- Alpha stimulation: peripheral vasoconstriction
What 2 inputs control Bronchoconstriction?
- Cholinergic Input (ANS)
- SNS Alpha Input
Drug classification:
Cromolyn
Nedocromil
Just memorize
Prophylactic (preventative): inhibts release of inflammatory mediators