Unit 4 - Immune System PART B

Question 1

Immune system has 2 anatomical components:

Answer 1

1) Lymphoid tissue &

2) The cells responsible for the immune response

Question 2

Primary lymphoid tissues

Answer 2

where leukocytes are produced

a. Thymus gland
b. Bone marrow
- both organs are sites where cells involved in the immune response form & mature

Question 3

Thymus gland

Answer 3

site of production of T lymphocytes

Question 4

Bone marrow

Answer 4

produces all other leukocytes

Question 5

Secondary lymphoid tissues

Answer 5

where leukocytes mature, proliferate, and interact with pathogens

a. Spleen
b. Lymph Nodes
c. Mucosal Associated Lymphoid Tissue (MALT)

Question 6

Spleen

Answer 6

Monitors blood - pathogens in blood exposed to active immune cells
i. Can be divided into 3 are:

Question 7

Spleen can be divided into 3 areas:

Answer 7

1) RED PULP
2) WHITE PULP
3) CAPSULE

Question 8

Red pulp

Answer 8

closely associated with blood vessels/sinuses; contains many macrophages that help to filter blood and destroy old RBCs;

Question 9

White Pulp

Answer 9

similar in structure to lymph nodes; composed mainly of lymphocytes

Question 10

Capsule

Answer 10

outer protective casing

Question 11

Lymph Nodes

Answer 11

monitor interstitial fluids via lymphatic system; also monitor blood (like the spleen)

• closely associated with capillaries of the CV system
  i. Similar structure to spleen (has a capsule)
  ii. Clusters of immune cells “meet and greet” pathogens that invade ISF and pathogens brought by blood vessels. :

Question 12

Spleen & Lymph Nodes are…

Answer 12

ENCAPSULED LYMPHOID TISSUES

both have fibrous collagenous capsule walls & immune cells positioned so that they monitor the EC compartment for foreign invaders

Question 13

Mucosal Associated Lymphoid Tissue (MALT)

Answer 13

diffuse lymphoid tissue lining digestive, respiratory, reproductive, urinary tracts. Includes tonsils, GALT (gut associated lymphoid tissue)

• in each location, the immune cells are positioned to intercept invading pathogens before they get into the general circulation

Question 14

Mucosal Associated Lymphoid Tissue (MALT) is…

Answer 14

UNENCAPSULATED DIFFUSE LYMPHOID TISSUES

- aggregations of immune cells that appear in other organs & tissues of the body

Question 15

GALT (gut associated lymphoid tissue)

Answer 15

• lies just under the epithelium of the esophages & intestines
• some authorities consider GALT to the body’s largest immune organ b/c of the large SA of the digestive tract equilibrium