Unit 3 - Blood PART A & B Flashcards

1
Q

Blood

A

is a connective tissue that is specialized for transport and exchange solutes and fluids

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2
Q

Blood consists of:

A

a. Plasma – suspension of water and solutes

b. Formed elements – cells

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3
Q

Volume is ~_ to _ liters in MEN, and ~_ liters in WOMEN (dependent on body size)

A

5

5.5

4

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4
Q

Plasma

A
  • makes up 1/4 of the ECF, the internal envir. that bathes cells & acts as a buffer b/t cells & the external envir.
  • fluid matrix of the blood, within which cellular elements are suspended
  • identical in composition to IF except for the presence of PLASMA PROTEINS
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5
Q

Plasma composed of:

A

a. Water (~90%)

b. Dissolved solutes, including:
i. Proteins
ii. Electrolytes
iii. Nutrients
iv. Gasses
v. Metabolic waste products (e.g. urea, creatinine)

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6
Q

How much % does WATER in plasma contribute?

A

~90%

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7
Q

What do the dissolved solutes in plasma include?

A

i. Proteins
ii. Electrolytes (e.g. Na+, Cl-, H+, K+, Ca2+, HCO3-)
iii. Nutrients (e.g. glucose, amino acids, lipids, vitamins)
iv. Gasses (e.g. O2, CO2, N2)
v. Metabolic waste products (e.g. urea, creatinine)

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8
Q

Proteins (within the dissolved solutes of plasma)

determines…

A

determines plasma colloid osmotic pressure (πC ) and can

act as a buffer to help maintain blood pH.

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9
Q

Proteins (within the dissolved solutes of plasma) includes:

A
  • Albumins
  • Globulins
  • Fibrinogen
  • Transferrin
  • Peptide/Protein Hormones
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10
Q

Albumins

A

60% of all proteins; primarily responsible for πC

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11
Q

Globulins

A

α, β globulins transport lipids, some metal ions and

hormrones; γ (gamma) globulins (immunoglobulins/antiboidies).

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12
Q

Immunoglobulins/antiboidies (within globulins)

A

syn. & secreted by SPECIALIZED BLOOD CELLS rather than by the liver

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13
Q

Fibrinogen

A

clotting protein

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14
Q

Transferrin

A

transports iron that is not part of hemoglobin

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15
Q

What makes most plasma proteins & secretes them into the blood?

A

LIVER

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16
Q

Electrolytes (within the dissolved solutes of plasma)

A

e.g. Na+, Cl-, H+, K+, Ca2+, HCO3-

17
Q

Nutrients (within the dissolved solutes of plasma)

A

e.g. glucose, amino acids, lipids, vitamins

18
Q

Gasses (within the dissolved solutes of plasma)

A

e.g. O2, CO2, N2

19
Q

Metabolic waste products (within the dissolved solutes of plasma)

A

e.g. urea, creatinine

20
Q

Presence of _____ in the plasma makes the osmotic pressure of the blood ______ than that of the IF. Explain

A

PROTEINS

HIGHER

  • this osmotic gradient tends to pull water from the IF into the capillaries & offset filtration out of the capillaries created by BP