Unit 3 Neurons and Human Brain Flashcards
What is the specialized cell that primarily makes up the brain?
Neurons
What is the function of a Neuron?
Communication cells, they send and receive neurotransmitters
The Action Potential causes the neuron to release a brain chemical, what are these called?
Neurotransmitters
List neurotransmitters covered in this lecture
Adrenaline/Epinephrine
Noradrenaline/Norepinephrine Dopamine
Serotonin
GABA
Acetylcholine
Glutamate
Endorphins
What is Adrenaline/Epinephrine?
Fight or flight neurotransmitter
What is Noradrenaline/Norepinephrine?
Concentration neurotransmitter
What is Dopamine?
Pleasure neurotransmitter
What is Serotonin?
Mood neurotransmitter
What is GABA?
Calming neurotransmitter
What is Acetylcholine?
Learning neurotransmitter
What is Glutamate?
Memory neurotransmitter
What are Endorphins?
Euphoria neurotransmitter
What is an example of a problem that can happen with Adrenaline/Epinephrine?
Panic attacks
What is an example of a problem that can happen with Noradrenaline/Norepinephrine?
ADHD
What is an example of a problem that can happen with Dopamine?
Addiction
What is an example of a problem that can happen with Serotonin?
Depression
What is an example of a problem that can happen with GABA?
Anxiety/ Sleep problems
What is an example of a problem that can happen with acetylcholine?
Learning disorders
What is an example of a problem that can happen with Glutamate?
Alzheimers
What is an example of a problem that can happen with Endorphins?
Bipolar
What does the semi-permeable membrane have embedded within it?
Ion channels
Which cell creates the myelin sheath?
(This is why each myelin sheath has it’s own nucleus)
Schwann’s cells
What do synaptic vesicles hold?
Neurotransmitters
What is the main body of the neuron called?
The Soma
All around the Soma of the Neuron are branch-like structures, what are they called?
Dendrites
What is the area labeled #1 of the Neuron called?
Dendrites (receivers)
What is the area labeled #2 on this image of the Neuron called?
The Soma or cell body
What is the area labeled #3 on this image of a neuron called?
Axon (the conducting fiber)
What is this area labeled #4 on the image of the neuron called?
Node of Ranvier
What is the area labeled #5 of this image of a neuron called?
Axon terminals (transmitters)
What is this area labeled #6 on the image of a neuron called?
Schwann’s cells (they make the myelin)
What is this area labeled #7 on the image of a neuron called?
Myelin sheath (insulated fatty layer that spreads up transmission)
What is this area labeled #8 on the image of the neuron called?
The nucleus
What is the long tube extending away from the Soma?
The Axon
What are the fatty segments along the axon called?
The myelin sheath
What are the spaces between the myelin sheath called?
The nodes of ranvier
What are the cells that make the myelin sheath called?
Schwann’s cells
What is the “skin” of the neuron called?
The semi-permeable membrane
What kind of cell is the Schwann’s cells?
A glial cell
What are the branch like structures at the end away from the neurons main body called?
Axon terminals (transmitters)
What do synaptic vesicles hold?
Neurotransmitters
Where are the synaptic vesicles located?
In the Axon terminal
How does the axon terminal get triggered to release the neurotransmitters?
With an action potential
What are ions?
Charged particles
What does Na+ stand for?
Sodium
What does K+ stand for?
Potassium
What does the neuron Soma do?
Holds the nucleus “brain” of the neuron cell
What does the neurons semi-permeable membrane do?
Is the “skin” of the neuron and has ion channels to allows some ions in
What does the Axon do?
It is a long tube where the electricity of an action potential travels
What does the myelin sheath do?
It is fatty segments along the axon which speed up the conduction of electrical transmission of an action potential
What do the nodes of ranvier do?
These are unmyelinated parts along the axon that allow the electrical transmission of an action potential to hop over myelin sheath and speed up transmission
What is visible in each segment of the myelin sheath?
Schwann cells
What is contained in Axon terminals?
Synaptic vesicles
What do synaptic vesicles do?
They hold neurtransmitters
What do dendrites do?
They have receptor sites to to receive neurotransmitters
What do receptor sites do?
Portals to receive neurotransmitters
What are the 5 stages of an action potential?
RESTING
1) Threshold
2) Depolarization
3) Repolarization
4) Hyperpolarization
5) Na+/K+ pump
RESTING
Which stage of an action potential is described:
Na+ out, K+ >in/<out; ~40mV?
Threshold, the first stage
Which stage of an action potential is described:
Na+ in, K+ in; +mV?
Depolarization, the second stage
Which stage of an action potential is described:
Na+ in, K+ out; -mV?
Repolarization, the third stage
Which stage of an action potential is described:
Too negative to communicate
Hyperpolarization, the fourth stage
Which stage of an action potential is described:
Na+ out, K+ >in/<out
The Na+/K+ pump, the fifth stage
What does Na+ out, K+ in&out; -70mV describe?
Resting, before and after an action potential stage
During chemical transmission, which neuron (pre-synaptic or post-synaptic) goes through the action potential process?
Pre-synaptic neuron
What role does the pre-synaptic neuron play in chemical transmission?
It “sends” the neurotransmitters into the synaptic gap and goes through the reuptake process
Where do the neurotransmitters go upon release?
They are “eaten up” my the Monamine Oxidase enzyme (MAO) in the synaptic gap
What is synaptic gap?
The space between neurons, they never touch
What does the pre-synaptic neuron do after it has successfully released neurotransmitters into the synaptic gap?
The Reuptake process
What is the process of recycling or repackaging neurotransmitters after successful transmission of neurotransmitters into the synaptic gap by pre-synaptic neurons
Reuptake process
Why do MAO enzymes “eat” left-over neurotransmitters in the synaptic gap? What purpose does this serve for the brain/neuron?
This is a regulation process helps maintain brain chemistry balance
Which neuron receives the neurotransmitters after they have gone through the synaptic gap?
Dendrites on the post-synaptic neuron
What does “lock and key” specific receptor sites on the post-synaptic neurons dendrites mean?
Dendrites receptor sites can only receive specific neurotransmitters
Differentiate the “excitatory” vs “inhibitory” impact on the post-synaptic neuron after chemical transmission
Excitatory - increases action potentials
Inhibitory - decreases action potentials
What is a synapse?
The non-physical connection between two neurons (neurons never touch)
What causes long-term potentiation between neurons?
When neurons communicate frequently
What happens because of long-term potentiation of a synapse?
The synapse gets stronger and causes synaptic pathways to form which is the “hard-working” of your brain (i.e. memories/knowledge, etc)
What is homeostasis?
A balanced, stable or steady state
What happens if your neurotransmitters don’t stay balanced?
You will start having symptoms of mental illness
What can happen to a synapse if a person’s pattern of thinking changes?
If you don’t use it, you lose it. Vice versa if you use it more it gets stronger
What is Down Regulation?
When receptor sites shut down if too much dopamine is present
Describe an example of how a drug produces downregulation
-Take a drug
-The reward center of your brain produces dopamine (DA) and impairs reuptake & MAO processes
- excessive DA (the high)
- DA receptor sites shut down
What do prescription psychotropic drugs help with?
If a brain doesn’t self-regulate, then a drug may be used to help create balance (I.e. increase or decrease neurotransmitters)
What does newer research suggest about the tendency to use drugs to balance brain chemistry compared to making lifestyle changes? (such as dietary, exercise and sleep habits)
that the impact of exercise, diet and sleep habits may due a better job of helping the brain regulate itself
Where does the brain get the protein, potassium, sodium, and other nutrients it needs to function properly?
Food