Unit 3: Membrane Transport and Functions Flashcards
This controls what enters and exits the cell to maintain homeostasis
Cell Membrane
This provides protection and support for the cell
Cell Membrane
What is the structure of the cell membrane?
- lipid bilayer
- hydrophilic phosphate head
- hydrophobic fatty acid tail
- proteins embedded in membrane
[…] and […] proposed in 1972 that the membrane is a mosaic of proteins dispersed within the bilayer, with only the hydrophilic regions exposed to water
- S.J. Singer
- G. Nicolson
The 6 membrane proteins
- integral proteins
- pumps
- channel proteins
- carrier proteins
- enzyme proteins
- receptor proteins
Membrane Protein
Make up 70% of cell membrane proteins, permanently embedded within the cell membrane
Integral Proteins
Membrane Protein
Transfer substances against concentration and electrical gradients using ATP
Pumps
Membrane Protein
Transfer substances down concentration and electrical gradients, opened and closed by “gates”
Channel Proteins
Membrane Protein
Involved in the transport of specific substances by changing shape when bound to certain substances
Carrier Proteins
Membrane Protein
Catalyze membrane reactions
Enzyme Proteins
Membrane Protein
Bear appropriate sites for recognition of specific ligands
Receptor Proteins
The 2 types of membrane proteins
- peripheral proteins
- integral proteins
Type of Membrane Protein
Bound to the surface of the membrane
Peripheral Proteins
Type of Membrane Protein
Penetrate the hydrophobic core
Integral Proteins
The 6 functions of cell membrane proteins
- transport
- enzymatic activity
- signal transduction
- cell-cell recognition
- intercellular joining
- attachment to cytoskeleton and extracellular matrix
Cell recognize each other by […]
binding to surface molecules (often containing carbohydrates)
HIV binds to this receptor protein to infect a cell
CCR5
These proteins allow passage of hydrophilic substances across the cell membrane
Transport Proteins