Unit 3 Flashcards
Diaphysis
Bone shaft, walls of compact bone, hollow medullary cavity, w/ yellow marrow in adults
Epiphysis
Enlarged ends, spongy bone w/ red marrow
Spongy (cancellous) bone
lightens load + maintains strength
Compact bone
Resists compression + provides more resistance
Medullary cavity
Hollow space in center of long bones that store bone marrow and allows blood vessels to pass through
Red marrow
Soft, spongy tissue found in the cavities of bones that produce blood cells
Yellow marrow
Made up of fat and found in the cavities of large bones, produce cartinge fat and bone
Endosteum
Line spongy bone and medullary cavity
Periosteum
Surrounds bone (except particular cartilage of epiphyses) entry of blood, lymph vessels + nerves
Epiphany seal plate
. Disc of cartilage that’s located at the ends of long bones in children and teen growth
What are the 2 types of bone formation?
Intramembranous and endochondral ossification
Zone of resting (reserve) cartilage
Inactive chodrocytes on epiphysis side
② zone of proliferation (growth zone)
Cartilage cells undergo mitosis, pushing the epiphysis away from diaphysis
③ zone of hypertrophy
Older cells enlarge
④ zone of calcification (destruction)
Matrix becomes calcified, cartilage cells die, matrix begins to detoriate
⑤ zone of bone formation (osteogende)
New bone formation occurs by osteoblasts (subsequently eroded by osteoblasts oblasts form medullary cavity)
Skeletal system function
Support, movement,protection, mineral/fat storage, hemotopolesis
Orthopedist
Muscle skeletal specialist
Long bones
Longer than wide, levers for muscle, (femur, radius, phalanges, meta carpals, etc.)
Short-cube like bones
Stability, support, gliding movements, (carpals and tarsals)
Flat thin and curved bone
Anchor muscles, protection (sternum,ribs, scapulae, cranial)
Irregular bone
Protection (vertebrae, facial bones)
Sesamoid
. Small and round, imbedded intends, protects tendons agal pression (patella)
Articulations
Site where bone meets bone (joints)
Projections
Attachment points for tendons/ligaments
Holes
Opening or groove for vessel/nerve passage
Osteocyte (bone cell)
Form osteoblast trapped in mature matrix
Osteoblast
Actively secretes matrix = bone makers
Osteogenic
Stem cells (mesenchyme in bones) - divide to produce osteoblasts
Bone matrix
Collagen fibers surrounded by hardened calcium salts (hydroxyapatite’s) mainly
Where is osteogenic found?
Cellular layer of periosteum
Osteon
Unit of compact bone
Lamellar
Layers of matrix b/h osteocytes
Central canal
Center of osteon , path for vessels/nerves ‘
Percolating canal
Path for vessels/nerves to adjacent
What is spongy bone composed of?
Trabecular (struts) = aligned along stress lines
Endochondral ossification
Most of skeleton starts as hyaline cartilage model w/perichondrium
Closed fracture
Skin intact
Open fracture
. Bone tears skin
Transverse
Straight across
Spiral
Result of twist, sports
Commented
Small
Closed reduction
Set w/o surgery
① step EO
Most of skeleton starts as hyaline cartilage model w/ perichondrium
② step of EO
Deep chodrocytes enlarge, matrix calcifies, cell die, matrix erodes
③ step of EO.
Capillaries penetrate cartilages/ bring osteogenic cells. Perichondrum->speriosteum
④ step of EO
Cartilage and chondrocytescontinue to grow at ends
⑤ step of EO
After birth, secondary ossification centers develop in epiphyses-remain spongy bone
⑥ step of EO
Cartilage remains at epiphyses (growth) plate
Fracture repairs stages (4)
Inflammation and hematoma, ② fibrocartilagenous internal callus formation, ③ bony callus formation ,④ healed fracture
Explain ① inflammation and hematoma (6-8hrs)
Inflammation followed by fracture hematoma (internal clot)
Explain ② fibrocartilagenous internal callus formation (48hrs after injury)
Chord oblasts and fibroblasts form endosteum connect bone internally w/ fibrocart., periosteal chondro. + osteoblasts form external callus of hyAline cartilage and bone
Explain ③ bony calves formation (several weeks)
Osteoclasts resort dead-bone, osteoblasts convert celli to spongy bone via endochonaral ossification
Explain ④ healed fracture (6-8wks)
Internal and external call unite, compact bone replaces songy on outer surface, remodeling continues
Nutrition and bone tissue
Calcium; calcium phosphate +ca carbonate = mineralized bone
What does exercise (stress) do to bones?
Bones become ideal size to handle stress, stimulates bone deposition, prevent osteoporosis
2nd nutrition and bone tissue
Vitamin D, needed to absorb ca, synthesized by skin w/uv
3rd nutrition and bone tissue
, Vitamin K, synergism w/ vitamin D
4th nutrition and bone tissue
Magnesium and fluoride, imbedded in matrix
Growth hormone
Responsible for growth before puberty
Thyroid hormone
Required for GH to work properly, stimulate growth
Sex hormones
Growth spurt at puberty, closure of epiphany seal plates
Calcitrol hormones
Fully activated vitamin D -ce absorption
Parathyroid hormone
Increase ca in blood, stimulate osteoblasts
What does PTH control?
Main control of blood calcium
Hypocalcemia (essay)
. Low Ca levels = poor blood clotting,❤️ stops, muscle failure, overactive nerves
If ca levels ↓… (Essay)
PTH release ↑ - osteoclasts reabsorb bone, kidney reabsorbs more ca, intestines increase absorption, Ca levels ↑
If ca levels ↑… (Essay)
- PTH release ↓ - all of the above reversed, ca levels decline
Bone density
Declines w/ age, bone density peaks at about 25-30 yrs of age
Osteoporosis
Bone thinning - make bones fragile and fracture, affects former
Axial
Skull and vertebral column, thoracic cage (rubs and sternum)
Appendicular
Pectoral girdle = (scapulae + clavicles,)’. Pelvic girdle
Human skull - 22 bones
Brain case (8 bones) surrounds brain, facial (14), parts of orbit and nasal cavity
Cranial fossa e
- Inside skull