Unit 2 (Week 6 Assignment Questions) Flashcards
Which of the following pathways occurs in the cytosol?
glycolysis
breakdown of pyruvate to an acetyl group
citric acid cycle
oxidative phosphorylation
all of the above
A
The net products of glycolysis are
6 CO2, 4 ATP, and 2 NADH.
2 pyruvate, 2 ATP, and 2 NADH.
2 pyruvate, 4 ATP, and 2 NADH.
2 pyruvate, 2 GTP, and 2 CO2.
2 CO2, 2 ATP, and glucose.
B
During glycolysis, ATP is produced by
oxidative phosphorylation.
substrate-level phosphorylation.
redox reactions.
all of the above.
both a and b.
B
Which organic molecule supplies a two-carbon group to start the citric acid cycle?
ATP
NADH
acetyl CoA
oxaloacetate
both a and b
C
The ability to diagnose tumors using [18F]-fluorodeoxyglucose (FDG) is based on the phenomenon that most types of cancer cells exhibit higher levels of
glycolysis.
pyruvate breakdown.
citric acid metabolism.
oxidative phosphorylation.
all of the above.
A
In the experiment of Racker and Stoeckenius, bacteriorhodopsin was oriented in such a way that it pumped H+ into a vesicle. Each vesicle actually contained many molecules of bacteriorhodopsin. How would the results of the experiment have been affected if 50% of the bacteriorhodopsin molecules pumped H+ into the vesicle and 50% pumped H+ out of the vesicles?
The same amount of ATP would be made in the presence of light, and no ATP would be made in the dark.
More ATP would be made in the presence of light, and no ATP would be made in the dark.
No ATP would be made in the presence of light, and no ATP would be made in the dark.
No ATP would be made in the presence of light, but some ATP would be made in the dark.
Some ATP would be made in the presence of light, and some ATP would be made in the dark.
C
Certain drugs, which are called ionophores, cause the mitochondrial membrane to be highly permeable to H+. How would such drugs affect oxidative phosphorylation?
Movement of electrons down the ETC would be inhibited.
ATP synthesis would be inhibited.
ATP synthesis would be unaffected.
ATP synthesis would be stimulated.
Both a and b would occur.
B
The source of energy that directly drives the synthesis of ATP during oxidative phosphorylation is the
oxidation of NADH.
oxidation of glucose.
oxidation of pyruvate.
H+ electrochemical gradient.
reduction of O2.
D
Compared with oxidative phosphorylation in mitochondria, anaerobic respiration in bacteria differs in that
more ATP is made.
ATP is made only via substrate-level phosphorylation.
O2 is converted to H2O2 rather than H2O.
something other than O2 acts as a final electron acceptor of the ETC.
both b and d occur.
D
When conditions in a muscle become anaerobic during strenuous exercise, why is it necessary to convert pyruvate to lactate?
to decrease NAD+ and increase NADH
to decrease NADH and increase NAD+
to increase NADH and increase NAD+
to decrease NADH and decrease NAD+
to keep oxidative phosphorylation running
B
The electron transport chain is so named because electrons are transported from one component to another. Describe the purpose of the ETC.
The purpose of the electron transport chain is to pump H+ across the inner mitochondrial membrane to establish an H+ electrochemical gradient. When H+ flow back across the membrane through ATP synthase, ATP is synthesized.
What causes the rotation of the γ subunit of ATP synthase? How does this rotation promote ATP synthesis?
The movement of H+ through the contact site between the c and a subunits causes the γ subunit to rotate. As it rotates, it sequentially alters the conformation of the β subunits, where ATP is made. This causes (1) ADP and Pi to bind with moderate affinity, (2) ADP and Pi to bind very tightly such that ATP is made, and (3) ATP to be released.
How is glucose breakdown regulated to avoid the overproduction of ATP and NADH? What would be some potentially harmful consequences if glucose metabolism was not regulated properly?
The phases of glucose metabolism are regulated in a variety of ways. For example, key enzymes in glycolysis and the citric acid cycle are regulated by the availability of their substrates and by feedback inhibition. The electron transport chain is regulated by the ATP/ADP ratio. Such regulation ensures that a cell does not waste energy making ATP when it is in sufficient supply. Also, the production of too much NADH is potentially harmful because at high levels it has the potential to haphazardly donate its electrons to other molecules and promote the formation of free radicals, highly reactive chemicals that damage DNA and cellular proteins.
Discuss the advantages and disadvantages of aerobic respiration, anaerobic respiration, and fermentation.
Fill In
Read more about PET scans in other sources. Which types of cancers are most easily detected by this procedure, and which types are not readily detected? Is the ability to detect cancer via a PET scan related to the level of oxygen within a tumor?
Fill In
Which of the following is the best description of the process of cellular respiration?
Multiple choice question.
A means to extract energy from organic molecules
A means to utilize ATP in cells
A means to extract energy from oxygen
A means to extract energy from inorganic molecules
A
The main product of cellular respiration is
Multiple choice question.
oxygen
ATP
carbon dioxide
organic molecules
B
Glucose contains covalent bonds that store a large amount of ______.
Multiple choice question.
water
kinetic energy
ATP
chemical energy
chemical energy
What is the order of glucose breakdown?
Glycolysis, breakdown of pyruvate, citric acid cycle, and oxidative phosphorylation
Which of the following are end products of glycolysis?
Multiple select question.
Pyruvate
Oxygen gas
ATP
NADH
Pyruvate
ATP
NADH
The metabolic reactions that a cell uses to get energy from food molecules and release waste products are collectively called ______.
Multiple choice question.
cellular respiration
chemical respiration
oxidative phosphorylation
glycolysis
cellular respiration
Glycolysis occurs in the ______.
Multiple choice question.
plasma membrane
mitochondrion
cristae membrane
cytosol
cytosol
The primary aim of cellular respiration is to produce molecules of __________ which provide energy to the cell.
ATP, adenosinetriphosphate, or adenosine triphosphate
The pyruvate molecule produced in glycolysis undergoes a reaction which results in the production of one __________ group and one CO2 molecule.
acetyl, acetyl CoA, or acetyl-CoA
The ______ bonds in glucose store large amounts of energy.
Covalent
During glycolysis, one molecule of
______, is broken down into two molecules of pyruvate, driving the synthesis of ATP.
Glucose
Select all that apply
What four pathways are involved in the breakdown of glucose to carbon dioxide and water?
Multiple select question.
Photosynthesis
Citric acid cycle
Oxidative phosphorylation
Breakdown of pyruvate
Glycolysis
Gluconeogenesis
Citric acid cycle
Oxidative phosphorylation
Breakdown of pyruvate
Glycolysis
Tumors provide a favorable environment for glycolysis because their internal regions tend to be deficient in ______.
Multiple choice question.
NAD+
glucose
oxygen
ATP
oxygen
Glycolysis is the breakdown of glucose into ______.
Multiple choice question.
two pyruvate molecules
six carbon dioxide molecules
two citric acid molecules
three acetyl groups
two pyruvate molecules
While glycolysis occurs in the ___________
in eukaryotic cells, the remaining steps of respiration occur in the ___________
of the cell.
Cytosol/mitochondria
True or false: Glycolysis occurs in the mitochondria.
True false question.
True
False
False
When a carbon dioxide is removed from pyruvate, the product is a(n) _______
group, which then attaches to coenzyme A.
Acetyl
What are the products of the breakdown of a single pyruvate molecule?
Multiple select question.
One ATP molecule
Two NADH molecules
One acetyl group
One CO2
Two acetyl groups
One NADH molecule
One acetyl group
One CO2
One NADH molecule
Glycolysis involves the breakdown of one molecule of glucose into ______.
Multiple choice question.
one molecule of pyruvate and one molecule of acetyl-CoA
one molecule of pyruvate and three molecules of CO2
three molecules of acetyl-CoA
two molecules of pyruvate
two molecules of pyruvate
In the first reaction of the citric acid cycle, oxaloacetate, which contains ______ carbons, is combined with acetyl-CoA, which contains ______ carbons in its acetyl group, to produce citric acid, which contains ______ carbons.
Multiple choice question.
3; 3; 6
3; 1; 4
5; 1; 6
4; 2; 6
4; 1; 5
2; 2; 4
4, 2, 6
True or false: Within tumors, glycolysis is favored under hypoxic conditions.
True false question.
True
False
True
What energy intermediates are produced in the citric acid cycle?
Multiple select question.
Pyruvate
Acetyl-CoA
NAD+
NADH
GTP
FADH2
NADH
GTP
FADH2
In order for cellular respiration to continue, the pyruvate produced in glycolysis must be transported into the ______.
Multiple choice question.
mitochondrion
stroma
electron transport chain
cytosol
mitochondrion
During cellular respiration, acetyl-CoA is formed during a reaction that also:
Multiple choice question.
attaches coenzyme A to pyruvate
reduces pyruvate
removes a CO2 from pyruvate
removes coenzyme A from pyruvate
removes a CO2 from pyruvate