UNIT 14 [2NDPART] - 14.4 & onwards, HOMEOSTASIS Flashcards
desc: homeostasis
the maintenance of a
constant internal environment
insulin _____ blood glucose
concentration
insulin
DECREASES
blood glucose concentration
Homeostasis always tries to …
keep a variable in our body at a set point using negative feedback
meaning
If a variable changes from the set point it will be detected by a receptor, transmitted by nerves and an effector will be activated to return the variable to its set point
examples
insulin / glucagon for homeostasis of blood sugar levels,
ADH for homeostasis of blood water levels
homeostasis of body temperature
Heat losses must ______ heat gains to maintain a constant body temperature
EQUAL
Role of Insulin in Homeostasis
here, internal conditions within the body…
need to be kept within set limits in order to ensure that reactions in body cells can function and therefore the organism as a whole can live
body will not function properly otherwise
Insulin is secreted into the blood at times when blood glucose levels are high
e.g.
(most often) directly after a meal
kidneys can only cope with a certain level of glucose in the blood
so if the level gets too high, …
to avoid this…
then…
glucose gets excreted and is lost in the urine
To avoid this, insulin temporarily converts excess glucose into glycogen in the liver and muscles
glycogen is converted back to glucose several hours later when blood glucose levels have dipped due to respiration in all tissues
The Concept of Negative Feedback
occurs when…
negative feedback ==> conditions change from the ideal or set point and returns conditions to this set point
if the level of something rises, …
control systems are switched on to reduce it again
if the level of something falls, …
control systems are switched on to raise it again
Negative feedback mechanisms => usually a continuous cycle of bringing levels down and then bringing them back up so that overall, …
they stay within a narrow range of what is considered ‘normal’
Blood Glucose Control - levels are controlled by a negative feedback mechanism invol. the production of two hormones -
insulin and glucagon,
made in the pancreas
when is (soluble) insulin produced
when blood glucose rises and stimulates liver and muscle cells to convert excess glucose into glycogen to be stored
when is glucagon produced
glycogen = insoluble
when blood glucose falls & stimulates liver & muscle cells to convert stored glycogen into glucose to be released into the blood
adrenaline also speeds up conversion of glycogen to glucose
EXAM TIP;; difference btwn glucagon & glYcOgen
Glucagon is the hormone
Glycogen is the polysaccharide glucose is stored as
what is Type 1 Diabetes
a condition/disorder where the blood glucose levels are not able to be regulated
as the insulin-secreting cells in the pancreas are not able to produce insulin/pancreas fail to produce sufficient insulin
so blood glucose levels are often far too high
treated by
injecting insulin
extra insulin causes
the liver to convert glucose into glycogen, which reduces the blood glucose level
Symptoms of diabetes
extreme thirst, weakness or tiredness, blurred vision, weight loss and loss of consciousness in extreme cases
what is required of someone w/ T1D
monitor their blood glucose levels throughout the day
as their levels of physical activity and their diet affect the amount of insulin needed
what they can do
help to control their blood glucose level by being careful with their diet -
=> eating foods that will not cause large increases in blood glucose level,
& by exercising, which can lower blood glucose levels due to increased respiration in the muscles
;;; not in syllabus
TYPE 2: body cells no longer respond to insulin
treatment for type 2: carbohydrate-controlled diet & an exercise regime
Temperature Control, thermoregulation, The Skin;
=> human body maintains the temperature at which enzymes work best, around ____
around 37°C
if body temperature increases over 37, enzymes will …
denature and become less effective at catalysing reactions such as respiration
Regulation…
which contains…
- is controlled by the brain
- brain contains receptors sensitive to the temperature of the blood
the skin has…
sends NERVOUS IMPULSES…
skin also has temperature receptors and sends nervous impulses to the brain via sensory neurones
brain responds to this information by …
sending nerve impulses to effectors in the skin to maintain the temperature
within a narrow range of the optimum, 37°C
what does fatty tissue do
Fatty tissue under the dermis acts as a layer of insulation to prevent too much body heat being lost through the skin
hypothalamus…
- thermoregulatory centre in the hypothalamus senses the temperature of the blood flowing through it
- also receives information via sensory neurones from heat receptors in the skin
If the core body temperature starts to rise the hypothalamus triggers responses which increase heat losses
If the core body temperature starts to fall the hypothalamus triggers responses which either reduce heat losses OR generate more heat
SUMMARY ;; increase in body temperature
- thermoreceptors in the hypothalamus and skin detect change
=> increased sweating, vasodilation, hairs lie flat against skin
==> decrease in body temperature
decrease in body temp
- thermoreceptors in the hypothalamus and skin detect change
==> vasoconstriction, shivering, skin hairs erect
==> increase in body temp
Responses to changes in temperature:
- WHEN WE ARE HOT
- SWEAT is secreted by sweat glands.
cools skin by evaporation. heat energy from the body is lost as liquid water in sweat becomes water vapour (state change)