Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

hellma lec > UNIT 1.2 STEM CELLs > Flashcards

UNIT 1.2 STEM CELLs Flashcards

1
Q

HEMATOPOIETIC STEM CELLS are capable of

A

○ Self-renewal,
○ Pluripotent
○ Give rise to differentiated progeny

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

megakaryocyte becomes

A

platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T lymphoblast becomes

A

T cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

B lymphoblast becomes

A

B cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Respond best to multiple cytokines

A

PROGENITOR CELLS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

much
more mature than progenitor cells

A

PROGENITOR CELLS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

all blood cells are derived
from a single progenitor stem cell

A

MONOPHYLETIC THEORY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

pre-T becomes

A

T lymphoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Progeny increasingly acquire specific differentiation markers and function

A

PROGENITOR CELLS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

megakaryoblast becomes

A

megakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

pronormoblast becomes

A

erythrocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Are multipotent

A

PROGENITOR CELLS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

megakaryocyte-erythrocyte progenitor becomes

A
  • pronormoblast
  • megakaryoblast
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

each of the blood cell lineages
is derived from its own unique stem cell

A

POLYPHYLETIC THEORY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

pre-B becomes

A

B lymphoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

myeloblast becomes

A
  • neutrophil
  • eosinophil
  • basophil
17
Q

Blast cells committed to unilinear differentiation

A

PRECURSOR CELLS

18
Q

Do not self-renew or have only an extremely limited
capacity

A

PROGENITOR CELLS

19
Q

Common myeloid progenitor becomes

A
  • granulocyte-monocyte progenitor
  • eosinophil-basophil progenitor
  • megakaryocyte-erythrocyte progenitor
  • mast cells
20
Q

granulocyte-monocyte progenitor becomes

A
  • myeloblast
  • monoblast
21
Q

Hematopoietic stem cells become

A
  • Common myeloid progenitor
  • common lympoid progenitor
22
Q

HEMATOPOIETIC STEM CELLS Fates:

A

○ Self-renewal
○ Differentiation
○ Apoptosis

23
Q

still replicate until near terminal differentiation

A

PROGENITOR CELLS

24
Q

eosinophil-basophil progenitor becomes

A

myeloblast

25
Q

common lympoid progenitor becomes

A
  • dendritic cell
  • Pre-B
  • Pre-T
  • Natural killer cells
26
Q

HEMATOPOIESIS have Unique interactions of:

A
  1. Pluripotential SC/ (HSC)
  2. Microenvironment
  3. Cytokines/Growth Factors
    a. Colony-stimulating factor
    b. Kit Ligand/Stem Cell Factor
    c. Interleukins
  4. EPO
  5. TBO (thrombopoietin)
27
Q

B cell becomes becomes

A

Plasma cells

28
Q

Respond best to one or 2 cytokines

A

PROGENITOR CELLS

29
Q

Do not self-renew

A

PROGENITOR CELLS

hellma lec (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions