Unit 11 - The Brain Flashcards
What determines intelligence in the human brain
Active synapses
A typical human brain has a volume of 1300 cc and weighs around
3 Pounds
When viewed superiorly, the cerebrum is divided into two halves, what are they
the left and right cerebral hemispheres
Each hemisphere may be further subdivided into five functional areas called
Lobes
The outer surface of an adult brain exhibits folds called
Gyri
The shallow depressions between the folds of the outer surface of the brain
Sulci
Two directional terms are often used to describe brain anatomy, what are they
Rostral - Toward Nose, synonymous with superior
Caudal - Toward Tail, synonymous with inferior
By the fifth week of embryonic development, a total of five regions appear, what are they
- Telencephalon - which eventually forms the cerebrum.
- Diencephalon - which eventually forms the
thalamus, hypothalamus, and epithalamus. - Mesencephalon - which forms a short section of the brain stem between the diencephalon and the pons.
- Metencephalon - which eventually forms the pons and
cerebellum. - Myelencephalon - which eventually forms the
medulla oblongata.
What grows rapidly and surrounds the diencephalon during the embryonic and fetal periods?
Telencephalon
As the future brain develops, its surface folds, especially in the telencephalon, leading to the formation of what
Adult sulci and gyri
What determines the boundaries of the brain’s cavities
The bends and creases that occur in the developing brain
What are necessary in order to fit the massive amount of brain tissue within the confines of the cranial cavity
The bends, creases, and folds in the telencephalon surface.
When do most of the gyri and sulci develop
Late in the fetal period
What two distinct tissue areas are recognized within the brain and spinal cord
Gray and White Matter
Gray matter houses what
(a) Motor neuron and interneuron cell bodies
(b) Dendrites
(c) Branching axon terminals
(d) Unmyelinated axons
White matter houses what
Myelinated axons, but also dendrites and
associated neuroglial cells.
How does White Matter derive its color
From the myelin in the myelinated axons
During brain development, an outer, superficial region of what forms from migrating peripheral neurons
gray matter
External sheets of gray matter, called what, cover the surface of most of the adult brain (the cerebrum and the
cerebellum)
Cortex
The white matter of the brain lies ______ to the gray matter of the cortex
This inner region of white matter is called what
Deep, Medulla
Sudden decelerations (i.e. - car crashes) can cause gray and white matter in the brain to what
To shear at the interface
The spinal cord has white matter as its outer layer and gray matter at its center, true or false?
True
The brain is protected and isolated by what multiple structures
- The bony cranium
- Connective tissue membranes, called “meninges”, surround and partition portions of the brain.
- Cerebrospinal fluid (CSF) acts as a cushioning fluid.
- The blood-brain barrier prevents the entry of harmful materials from the bloodstream.
What do the meninges do for the brain
- separate the soft tissue of the brain from the bones of the cranium
- enclose and protect blood vessels that supply the brain
- contain and circulate cerebrospinal fluid.
- In addition, some parts of the cranial meninges form some of the veins that drain blood from the brain.
The three connective tissue layers of the meninges
- pia mater (Innermost layer)
- arachnoid (Internal to Dura Mater)
- dura mater (Most external layer of meninges)
Which tissue layer of meninges is composed of delicate connective tissue that is highly vascularized and which
tightly adheres to the brain and follows every contour of the brain surface
Pia Mater
Meninges tissue layer that means “like a spider or resembling a spider’s web”, and this meninx is so named because it is partially composed of a delicate web of collagen and elastic fibers
Arachnoid
What is immediately deep to the arachnoid
The subarachnoid space
The spiderweb-like extensions of the arachnoid extend through this space from the arachnoid to the underlying pia mater
What’s between the arachnoid and the overlying dura mater
A potential space called the “subdural space”.
What is composed of tough, dense irregular connective tissue that has two fibrous layers
Dura Mater
What’s the strongest of the meninges
Dura Mater
Within the cranium, the dura mater is composed of what two layers
meningeal layer - lies deep to the periosteal layer
periosteal layer - the more superficial layer, forms the periosteum on the internal surface of the cranial bones..
The meningeal layer is usually fused to the periosteal layer, except in specific areas where the two layers separate to form large, blood-filled spaces called
dural venous sinuses
Dural venous sinuses are typically triangular in cross section, and unlike most other veins, they do not have valves to regulate the venous flow
True
The dural venous sinuses are, in essence, large veins that drain blood from the brain and transport the blood to the ________
Internal jugular veins
The dura mater and the bones of the skull may be separated by the potential _______
Epidural space
What does the Epidural Space contain
It contains the arteries and veins that nourish the meninges and bones of the cranium.
Under normal (healthy) conditions, the epidural space ________
Is not a space at all
What makes the epidural space to become a real space and fill with fluid or blood
Trauma or disease
A pooling of blood outside of a vessel is referred to as what
Hematoma
Occurs as a result of a ruptured artery, when a pool of blood forms in the epidural space of the brain, usually due to a severe blow to the head
Epidural hematoma
A hemorrhage that occurs in the subdural space between the dura mater and the arachnoid mater
Subdural hematoma
This type of hematoma typically results from ruptured veins caused by either fast or violent rotational motion of the head.
Subdural hematoma
How do you treat Subdural and Epidural Hematomas
accumulated blood removed by surgically drilling a hole in the skull, suctioning out the blood, and ligating (tying off) the bleeding vessel.
Flat partitions of the meningeal layer of the dura mater that extend into the cranial cavity at several locations
Septa
Double layers of dura mater are called
Cranial dural septa
Cranial dural septa do what
Separate specific parts of the brain and provide
additional stabilization and support for the entire brain.
The four cranial dural septa
- Falx Cerebri
- Tentorium Cerebelli
- Falx Cerebelli
- Diphragma Sellae
The largest of the four dural septa
Falx Cerebri
This large, sickle-shaped vertical fold of dura mater, located in the midsagittal plane, projects into the longitudinal fissure between the left and right cerebral hemispheres
Falx Cerebri
The anterior attachment site for the falx cerebri
the crista galli of the ethmoid bone
The posterior attachment site for the falx cerebri
the superior portion of the tentorium cerebelli
Running within the margins of the falx cerebri are several _______
dural venous sinuses
a horizontally-oriented fold of dura mater that separates the occipital lobe and temporal lobes of the cerebrum from the cerebellum
tentorium cerebelli
What runs within the posterior border of the tentorium cerebelli
dural venous sinus
The anterior surface of the tentorium cerebelli has a small gap or opening called
the “tentorial notch” (“tentorial incisure”) to allow for the passage of the brainstem
Extending into the midsagittal line inferior to the tentorium cerebelli is the _______ a sickle-shaped vertical partition that divides the left and right
cerebellar hemispheres
falx cerebelli
What runs in the posterior vertical border of the falx cerebelli
A tiny dural venous sinus
The smallest of the dural septa is the ______
diphragma sellae
forms a “roof” over the sella turcica of the sphenoid
bone
diphragma sellae
A small opening within it allows for the passage of a thin stalk that attaches the pituitary gland within the sella turcica to the base of the hypothalamus located just
above.
diphragma sellae
Cavities or expansions within the
brain that are derived from the lumen (opening) of the embryonic neural tube
The brain “ventricles”
There are four ventricles in the brain, all of which contain cerebrospinal fluid, what are they
- The two “lateral ventricles” - (the first is in the right cerebral hemisphere while the second is in the left cerebral hemisphere)
- The “third ventricle” - a smaller chamber located within the diencephalon
- The “fourth ventricle” - shaped like a tetrahedron and is located between the pons and the cerebellum.
What’s the thin medial partition called that separates the two lateral ventricles in the right and left cerebral hemispheres
the “septum pellucidum”
Each lateral ventricle communicates with what ventricle
the third ventricle
Which ventricle narrows at its inferior end before it merges with the “central canal” in the spinal cord
The fourth ventricle
a clear, colorless liquid that circulates in the ventricles and subarachnoid space
Cerebrospinal fluid
What bathes the exposed surfaces of the central nervous system and completely surrounds it
Cerebrospinal fluid (CSF)
CSF performs several important functions, what are they
- Provides buoyancy so that the brain floats, thereby reducing its apparent weight by more than 95% and preventing it from being crushed under its own weight
- Provides protection by creating a liquid cushion to protect the brain from sudden movements
- Provides environmental stability by transporting nutrients, chemical messengers, and by removing wastes
Removal of what during spinal taps, causes many persons to complain of headaches, caused in part by a loss of this cushioning buoyancy
CSF
refers to the acute brain damage that occurs as a result of an accident or trauma
Traumatic brain injury (TBI)
The most common type of TBI
Concussion
a TBI where there is bruising of the brain due to trauma that causes blood to leak from small vessels into the subarachnoid space
Contusion
a rare but serious condition called _______, where an individual experiences a second brain injury prior to the resolution of the first injury, and develops severe brain swelling and possible death as a result
second impact syndrome (SIS)