Unit 1-Genomic Sequencing Flashcards
The sequence of nucleotide bases can be determined for individual genes and entire genomes.
Genomic sequencing
The comparison of sequence data using statistics and computers
Bioinformatics
Data used to study the evolutionary relatedness among groups of organisms
Phylogenetics
Sequence divergence is used to estimate time since lineages diverged.
Molecular clocks
The sequence of events during evolution can be determined using these sources of information.
Sequence data and fossil evidence
The name given to the three broad groups of organisms
Domains
Three domains of life
Bacteria, archaea and eukaryotes.
Reveals that many of the same genes are found across different organisms
Conservation of genes
The analysis of an individual’s genome which could lead to personalised medicine
Personal genomics
Potential to treat individuals. Comes with difficulties as it is hard to distinguish between harmful and neutral mutations
Personalised medicine
Species that are important in research
Model organisms
Benefit of sequencing of disease-causing organisms.
Help with accurate diagnosis
Benefit of sequencing pest species
Help identify risks and lead to specific methods of control being developed rather than general pesticides
Benefit of sequencing of model organisms such as fruit flies, C. elegans nematodes or zebra fish.
Can be used in medical research in place of mammals (reducing ethical concerns and costs).