Unit 1

Question 1

meaning of haima

Answer 1

blood

Question 2

meaning of logos

Answer 2

study

Question 3

the science that deals with blood

Answer 3

hematology

Question 4

who discovered the closed circulation of blood

Answer 4

william harvey (1628)

Question 5

first description of rbc

Answer 5

anton van leeuwenhoek (1674)

Question 6

father of hematology

Answer 6

william hewson

Question 7

first successful transfusion of human blood to a patient performed

Answer 7

james blundell (1818)

Question 8

first description of Hodgkin disease

Answer 8

thomas hodgkin (1832)

Question 9

intro of microscopic analysis of blood

Answer 9

gabriel andral (mid 1880s)

Question 10

first description of leukemia

Answer 10

rudolf virchow (1868)

Question 11

invention of novel blood cell staining techniques

Answer 11

paul ehrlich (1878)

Question 12

first description of phagocytosis

Answer 12

elie metchnikoff (1882)

Question 13

first definitive and precise description of the platelet

Answer 13

julius bizzozero (1882)

Question 14

First major guide to examination of blood

Answer 14

Richard Cabot (1898)

Question 15

Discovery of blood groups, A, B, AB, and O via isoagglutination reactions

Answer 15

Karl Landsteiner (1901)

Question 16

First description of syndrome of polycythemia vera

Answer 16

william osler (1903)

Question 17

First description of sickle cell disease

Answer 17

James Herrick (1910)

Question 18

First description of Glanzmann thrombasthenia as a defect in platelet function

Answer 18

Eduard Glanzmann (1918)

Question 19

First description of thalassemia

Answer 19

Thomas Cooley (1925)

Question 20

First description of von Willebrand disease

Answer 20

erik von willebrand (1926)

Question 21

Classic report of liver as first effective treatment of pernicious
anemia; first ever demonstration of a successful treatment

Answer 21

george minot (1926)

Question 22

First description of Fanconi syndrome

Answer 22

guido fancon (1927)

Question 23

Hematocrit technique refined

Answer 23

maxwell wintrobe (1929)

Question 24

identification of role of intrinsic factor in pernicious anemia

Answer 24

william castle (1929)

Question 25

a highly specialized tissue, which along with the circulatory system

Answer 25

blood

Question 26

an average human possesses how many liters of blood?

Answer 26

5 liters

Question 27

blood volume for adult male

Answer 27

5-6 liters

Question 28

blood volume for adult female

Answer 28

4-5 liters

Question 29

blood volume for newborns

Answer 29

250-350 ml

Question 30

ph of blood

Answer 30

7.35-7.45

Question 31

specific gravity of blood

Answer 31

1.055

Question 32

viscosity of blood

Answer 32

3.5 - 4.5x thicker than water

Question 33

dark red

Answer 33

venous blood (unoxygenated)

Question 34

bright red

Answer 34

arterial blood (oxygenated)

Question 35

mixture of venous and arterial blood

Answer 35

capillary blood

Question 36

vivo appearance

Answer 36

inside the body, liquid

Question 37

vitro appearance

Answer 37

outside the body, liquid to solid

Question 38

also known as erythrocytes

Answer 38

red blood cells

Question 39

3 main functions of blood

Answer 39

transportation, protection and regulation

Question 40

yellow layer of clotted blood

Answer 40

serum

Question 41

this contains fibrinogen, yellow layer of unclotted blood

Answer 41

plasma

Question 42

whitish layer

Answer 42

buffy coat

Question 43

normal value of rbc for adult male

Answer 43

4.20-6.00x1012/L

Question 44

normal value of rbc for adult female

Answer 44

3.80-5.20x1012/L

Question 45

increased RBCs

Answer 45

erythrocytosis

Question 46

decreased RBCs

Answer 46

erythrocytopenia

Question 47

decreased rbc hemoglobin concentration

Answer 47

anemia

Question 48

increased rbc-may lead to hyper viscosity

Answer 48

polycythemia

Question 49

function of rbc

Answer 49

transport oxygen and carry carbon dioxide away

Question 50

also known as leukocytes and it defends body against infections

Answer 50

wbc

Question 51

decreased wbc count

Answer 51

leukopenia

Question 52

increased wbc count

Answer 52

leukocytosis

Question 53

also known as thrombocytes and these major cells controls hemostasis

Answer 53

platelets

Question 54

hematologists refer to them as cell fragments

Answer 54

platelets