Unit 1 Flashcards
meaning of haima
blood
meaning of logos
study
the science that deals with blood
hematology
who discovered the closed circulation of blood
william harvey (1628)
first description of rbc
anton van leeuwenhoek (1674)
father of hematology
william hewson
first successful transfusion of human blood to a patient performed
james blundell (1818)
first description of Hodgkin disease
thomas hodgkin (1832)
intro of microscopic analysis of blood
gabriel andral (mid 1880s)
first description of leukemia
rudolf virchow (1868)
invention of novel blood cell staining techniques
paul ehrlich (1878)
first description of phagocytosis
elie metchnikoff (1882)
first definitive and precise description of the platelet
julius bizzozero (1882)
First major guide to examination of blood
Richard Cabot (1898)
Discovery of blood groups, A, B, AB, and O via isoagglutination reactions
Karl Landsteiner (1901)
First description of syndrome of polycythemia vera
william osler (1903)
First description of sickle cell disease
James Herrick (1910)
First description of Glanzmann thrombasthenia as a defect in platelet function
Eduard Glanzmann (1918)
First description of thalassemia
Thomas Cooley (1925)
First description of von Willebrand disease
erik von willebrand (1926)
Classic report of liver as first effective treatment of pernicious
anemia; first ever demonstration of a successful treatment
george minot (1926)
First description of Fanconi syndrome
guido fancon (1927)
Hematocrit technique refined
maxwell wintrobe (1929)
identification of role of intrinsic factor in pernicious anemia
william castle (1929)
a highly specialized tissue, which along with the circulatory system
blood
an average human possesses how many liters of blood?
5 liters
blood volume for adult male
5-6 liters
blood volume for adult female
4-5 liters
blood volume for newborns
250-350 ml
ph of blood
7.35-7.45
specific gravity of blood
1.055
viscosity of blood
3.5 - 4.5x thicker than water
dark red
venous blood (unoxygenated)
bright red
arterial blood (oxygenated)
mixture of venous and arterial blood
capillary blood
vivo appearance
inside the body, liquid
vitro appearance
outside the body, liquid to solid
also known as erythrocytes
red blood cells
3 main functions of blood
transportation, protection and regulation
yellow layer of clotted blood
serum
this contains fibrinogen, yellow layer of unclotted blood
plasma
whitish layer
buffy coat
normal value of rbc for adult male
4.20-6.00x1012/L
normal value of rbc for adult female
3.80-5.20x1012/L
increased RBCs
erythrocytosis
decreased RBCs
erythrocytopenia
decreased rbc hemoglobin concentration
anemia
increased rbc-may lead to hyper viscosity
polycythemia
function of rbc
transport oxygen and carry carbon dioxide away
also known as leukocytes and it defends body against infections
wbc
decreased wbc count
leukopenia
increased wbc count
leukocytosis
also known as thrombocytes and these major cells controls hemostasis
platelets
hematologists refer to them as cell fragments
platelets