Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology > Erythropoiesis > Flashcards

Erythropoiesis Flashcards

1
Q

the process of rbc production

A

erythropoiesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

rbc production normally occurs in?

A

bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

adult hematopoiesis production sites

A

verterbrae, ribs, sternum, skull and proximal ends of the femur and humerus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

formal name of rbc

A

erythrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

nucleated precursors in the bone marrow

A

erythroblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

refers to developing nucleated cells with normal appearance

A

normoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

abnormal appearance (large size) of the developing nucleated cells in megaloblastic anemia

A

megaloblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

days required to produce a mature rbc from the BFU-E

A

18-21 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

the color of rbc changes when it matures, it turns from blue to _______ and then ______.

A

gray and pink

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

it is when globin production begins

A

pronormoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

detectable hemoglobin occurs

A

basophilic normoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

last stage in which the cell is capable of undergoing mitosis

A

polychromatic normoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

salmon-pink color of the cytoplasm reflects nearly complete HEMOGLOBIN production

A

orthocromic normoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

in polychromatic erythrocyte, it can be stained using __________ or ____________.

A

methylene blue or brillian cresyl blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

matured erythrocyte remains active in the circulation for how many days?

A

120 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

describes the dynamics of rbc production and destruction

A

erythrokinetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

collection of all stages of erythrocytes in the body

A

erythron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

cells in circulation

A

rbc mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

promote early release of reticulocytes

A

erythropoietin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

deliver and transport of oxygen DOES NOT REQUIRE ENERGY

A

erythrocyte metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

responsible for 90% of ATP

A

anaerobic glycolitic pathway (embden meyerhof pathway)

22
Q

responsible for 10% ATP, also known as hexose monophosphate pathway

A

pentose phospate pathway

23
Q

able to convert oxidized heme iron to its reduced state

A

methemoglobin reductase pathway

24
Q

necessary for the facilitation of oxygen delivery to the tissues

A

rapaport-luebering pathway

25
Q

prevents loss of rbc membrane

A

deformability

26
Q

prevent colloid hemolysis

A

permeability

27
Q

cell aging

A

senescence

28
Q

extravascular hemolysis occurs in which organ?

A

spleen

29
Q

erythrocyte death as a nonnucleated cell version of apoptosis

A

eryptosis

30
Q

when the iron is removed from the heme, it can be stored in the macrophage as __________until transported out

A

ferritin

31
Q

carry oxygen and c02

A

hemoglobin

32
Q

carries Fe to developing RBCs

A

transferrin

33
Q

produced on specific ribosomes in the cytoplasm of RBCs

A

globin

34
Q

molecular strucure of gower 1

A

2 zeta, 2 epsilon

35
Q

molecular strucure of gower 2

A

2 alpha, 2 epilson

36
Q

molecular strucure of portland

A

2 zeta, 2 gamma

37
Q

molecular strucure of fetal (HbF)

A

2 alpha, 2 gamma

38
Q

molecular strucure of HbA-1

A

2 alpha, 2 beta

39
Q

molecular strucure of HbA-2

A

2 alpha, 2 delta

40
Q

stage of life of gower 1, gower 2 and portland

A

embryonic

41
Q

stage of life of fetal (HbF), HbA-1 and HbA-2

A

newborn & adult

42
Q

range of HbA-1 in adults

A

92%-95%

43
Q

range of HbA-2 in adults

A

2%-3%

44
Q

range of HbF in adults

A

1%-2%

45
Q

1g Hb is equals to

A

1.34 mL of oxygen

46
Q

the affinity of Hb for oxygen depends on _______________

A

partial pressure of oxygen

47
Q

the amount of oxygen needed to saturate 50% of hemoglobin is called

A

P50 value

48
Q

P50 value ranges normally around ________

A

27 mmHg

49
Q

factors causing the odc to shift to the right

A

increase co2, acidity, dpg, temperature

50
Q

shifts to curve to the left or right occur if there are changes in the pH of blood

A

bohr effect

51
Q

alkalosis, methemoglobenomia, increased carboxyhemoglobin

A

shift to the left

52
Q

high fever, acidosis, conditions that produces hypoxia

A

shift to the right

Hematology (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions