ulcerative colitis Flashcards
1
Q
M:F ratio?
A
M=F
2
Q
peak age?
A
20-30yrs and 70-80yrs
3
Q
spread of UC?
A
can be localised to rectum - i.e. proctitis
more commonly - spreads proximally to rectum
4
Q
involvements of UC?
A
appendix
10% cases involve pancolitis
5
Q
5 pathological features of UC?
A
LB only continuous pattern of inflammation pseudopolyps ulceration serosal surface is minimal or no inflammation
6
Q
key histological features of UC?
A
NO GRANULOMAS cryptitis/ crypt abscesses mucosal atrophy pseudopolyps limited to mucosa and submucosa submucosal fibrosis
7
Q
4 complications of UC?
A
malignancy
haemorrhage
perforation
toxic dilatation
8
Q
when do UC patients have higher risk of developing malignancy?
A
pancolitis > 10yrs
9
Q
UC vs CD?
A
CD: colon and ileum affected skip lesions thickened wall moderate fibrosis transmural inflammation
UC: colon only diffuse distributions thin wall mild fibrosis only mucosa is inflammation
10
Q
diagnosis of UC?
A
pANCA blood test
11
Q
key difference between CD and UC for exam qu?!
A
CD - any part of GI tract
UC - limited to colon
