large bowel malignancy (neoplasia) Flashcards
1
Q
result of high grade dysplasia?
A
malignancy
2
Q
type of dysplasia is more common?
A
low grade
3
Q
risk factors for colorectal carcinoma?
A
lifestyle
FH
UC
Crohn’s
4
Q
genetic associations with colorectal carcinoma?
A
FAP
HNPCC
Peutz-Jeghers
5
Q
which subtype of colorectal carcinoma is most common?
A
adenocarcinoma (98%)
6
Q
signs and symptoms of right sided colorectal adenocarcinoma?
A
anaemia vague pain weakness obstruction polypoid
7
Q
signs and symptoms of left sided colorectal adenocarcinoma?
A
annular lesion - “napkin ring”
bleeding
altered bowel habit
obstruction
8
Q
prognosis for colorectal adenocarcinoma?
A
TNM staging
Duke’s
9
Q
TNM staging?
A
T - 1-4
N - 1-2
M - 0-1
10
Q
5 stages of Duke’s?
A
A B1 B2 C D
11
Q
which stage of dukes does metastases occur?
A
C (stage 4)
12
Q
4 things used for prognosis?
A
TNM staging
Duke’s
extramural venous invasion
resection
