radiation colitis Flashcards
1
Q
definition?
A
injury to the colon caused by radiation therapy
2
Q
what is RC usually associated with?
A
pelvic radiotherapy,
sometimes treatment for prostate cancer or cervical cancer
3
Q
4 symptoms?
A
anorexia
abdominal cramps
diarrhoea
malabsorption
4
Q
what is the amount of damage dependent on?
A
the dose of radiotherapy
5
Q
which cells are especially targeted?
A
actively dividing cells, esp. blood vessels and crypt epithelium
6
Q
differential for chronic RC?
A
IBD
7
Q
4 histological features of RC?
A
bizarre cellular changes
inflammation - crypt abscesses and eosinophils
ulceration
necrosis
