UKMLA Ophthalmology Flashcards
Which ethnicity is more prone to developing primary open-angle glaucoma?
Black Africans
What is the characteristic visual defect associated with Primary Open Angle Glaucoma?
Halos and tunnel vision
PAINLESS visual loss of the peripheral field
What is the fundoscopy finding associated with Primary Open Angle Glaucoma?
Cupping of the optic disc with a thin neuroretinal rim
What is the gold-standard investigation indicated to diagnose Primary Open Angle Glaucoma?
Goldmann applanation tonometry - measures intraocular pressure
What is the first line topical drug for the management of Primary Open Angle Glaucoma?
Topical prostaglandin analogue e.g., latanoprost
What is the mechanism of action of prostaglandin analogues
Increases aqueous outflow
Hypertrichosis is an adverse effect associated with which drug implicated in the management of Primary Open Angle Glaucoma?
Prostaglandin analogues
What is the mechanism of action of beta-blockers in the management of Primary Open Angle Glaucoma?
Reduces aqueous production
What is the indication for selective laser trabeculoplasty or surgery for the management of Primary Open Angle Glaucoma?
if IOP >24
What is the clinical difference in visual loss presentation between closed-angle versus open-angle glaucoma?
Closed angle = painful
A fixed mid-dilated pupil is associated with which type of glaucoma?
Closed-angle glaucoma
What is the clinical presentation of closed-angle glaucoma?
- Acute red, painful eye
- Hazy cornea
- Corneal oedema
- Blurred vision
- Decreased visual acuity
- Worse with mydriasis (e.g., watching TV in a dark room)
- Haloes around lights
- Lacrimation
- Firm eyeball
- Fixed mid-dilated pupil
Which investigation is indicated in closed-angle glaucoma to visualise the angle?
- Gonioscopy
What is the first line management of closed-angle glaucoma?
- Emergency (same day) referral to ophthalmologist
+ miotic agent e..g, pilocarpine
How does pilocarpine work?
Causes contraction of the ciliary muscle to open the trabecular meshwork