UC + crohns hard Flashcards
inducing remission - crohns - severe
- oral prednisolone
- IV hydrocortisone
inducing remission - crohns - moderate
buodisonide
EEN
maintaining remission - crohns
azathioprine
mercathioprine
methotrexate
inflimamab
adalimumab
inducing remission - UC - severe
IV corticosteroid
IV cyclosporin
inducing remission - UC - moderate
aminosalciylate 5ASA eg mesalazine
corticosteroids
maintaining remission UC
aminoasalcatate
azathioprine
mercathioprine
TNF-a inhibitors
a-4/B-7 integrin inhibitor
JAK inhibitor
high risk complication of crohns
renal stones
age of crohns vs US
crohns:
- 15-30 + 60-80
UC:
- 15-25 + 55-65
crohns vs UC tests and results
Crohns:
- serum ACE is raised
- ESR/CRP raised
- feacal calprotectin - >90%
- raised WCC
- anaemia
- low albumin
- thrombocytosis
- P-ANCA -
- kantor string sign
UC:
- anaemia
- ESR/CRP
- faecal calprotectin
- P-ANCA +
- ECG - AF
- lead pipe colon
with what drugs do you need to measure thiopurine methyltransferase for - bone marrow suppression
azathioprine
mercaptopurine
with what drugs do you need to conduct chest xray bc of risk of reactivating latent TB
methotrexate + biologics
name the surgeries used in managing peri-anal fistula
drainage seton
fistulotomy
common happening after crohns ileum surgery
- decreased vitamins, minerals and fat absorption
- presents with diarrhoea and fatty stools
- short bowel syndrome
environmental UC aetiology
- milk
- medications
- NSAIDs
- oral contraceptive pill
name of severity grading criteria
truelove and watts
truelove and watts grading criteria
mild
- < 4 bowel movements a day
- small amount of blood
- no temperature
- no bpm>90
- na anaemia
- ESR >/= 30
moderate
- 4-6 bowel movements per day
- amount of blood between mild and severe
- no temperature
- no pulse >90
- no anaemia
- ESR </= 30
severe
- 6+ bowel movements per day
- visible blood
- temperature >37.8
- pulse >90
- anaemia ,10g/100mL
- ESR > 30
truelove and watts grading criteria severe temperature level
> 37.8
truelove and watts grading criteria severe pulse rate
> 90
truelove and watts grading criteria severe anaemia level
10/100mL
truelove and watts grading criteria severe ESR rate
> 30
pancrotocectomy types
- ilostomy
- ileo-anal anastomosis