U1: INTRO TO MOLBIO AND DIAGNOSTICS

Question 1

This refers to biological activity at the molecular level.

Answer 1

Molecular Biology

Question 2

This is the field that studies composition, structure, interaction of cell molecules, which includes nucleic acids and proteins that carry out biological processes essential for cell function and mainteinance.

Answer 2

Biology

Question 3

Why is molecular biology important?

Answer 3

Mixture of both biology and chemistry

Question 4

The devlopment of molecular biology started with?

Answer 4

Genomics

Question 5

DNA

Answer 5

detecting the genes

Question 6

RNA

Answer 6

detecting the expression

Question 7

Proteins

Answer 7

detecting if gene possesses a product

Question 8

How many genes are there in the human body?

Answer 8

25,000

Question 9

Molecular techniques:

Answer 9

• Polymerase Chain Reaction
• Molecular cloning
• Gel electrophoresis
• Macromolecule blotting and probing
• Microarrays
• Allele-specific oligonucleotide

Question 10

Most common molecular technique

Answer 10

PCR

Question 11

This blot detects DNA.

Answer 11

Southern

Question 12

This blot detects RNA.

Answer 12

Northern

Question 13

This blot detects proteins.

Answer 13

Western

Question 14

The one who developed Southern Blot is?

Answer 14

Edwin Southern

Question 15

This is not generally translated, but it is the post translation of proteins.

Answer 15

Eastern Blot

Question 16

These are the 2 world’s best publications who published the initial sequence in 2001.

Answer 16

Nature and Science

Question 17

Final draft of Human Genome Project was published on?

Answer 17

2003

Question 18

This term is synonymous to selection of therapeutic regimens and tailor fit to individual patients.

Answer 18

Personalized Medicine

Question 19

This refers to susceptibility test aiming at a low risk population.

Answer 19

Genetic Screening

Question 20

This refers to analysis of DNA or biomarkers for evaluation of one or more genetic risk factors for a particular disease or disease group.

Answer 20

Genetic Testing

Question 21

T/F: There are many factors that affect overall composition or expression.

Answer 21

True