U&E: Flashcards

1
Q

Creatinine:

Where is creatine produced from?

What is it used for?

What is it converted which allows it to be broken down to produce ATP and creatinine (waste product)?

A

Creatine is produced in the liver

Fast twitch muscle fibres

Creatine phosphate

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2
Q

Urea:

What happens in the urea cycle?

What can cause a raised urea?

What causes a lowered urea - just read

A

Ammonia is converted to urea

Dehydration 
GI bleed - break down of blood 
Increased protein breakdown (surgery, trauma, infection, malignancy) 
High protein intake 
Drugs 

Malnutrition
Liver disease
Pregnancy

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3
Q

Potassium:

What controls its levels?

Why is it when someone has acidosis, they may also have hyperkalaemia?

A

Aldosterone at the DCT = increases secretion

Due to potassium and hydrogen ions competing for the same transporter in the kidneys

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4
Q

Who can have a out of range blood test that would be normal for them?

A
Bodybuilders 
Those with amputations - less muscle mass 
Pregnancy 
Elderly 
Meds - trimethoprim 9
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