types of T cells and antibodies Flashcards
th1 polarising cytokine from APC
IL-12
Th2 polarising cytokine from APC
IL-4
Th17 polarising cytokine from APC
IL-6
IL-21
Tfh polarising cytokine from APC
IL-6
TGF beta
IL-23
Treg polarising cytokine from APC
TGF beta
Th1 transcription factor
T-bet
th2 transcription factor
GATA3
Th17 transcription factor
ROR gamma T
Tfh transcription factor
Bcl6
T reg transcription factor
FoxP3
Th1 cytokines produced
IFN gamma
Th2 ytokines produced
IL-4
IL-5
IL-13
Th17 cytokines produced
IL-17
IL-22
Tfh cytokines produced
IL-21
IL-4 or IFN gamma
T reg cytokines produced
IL-10
TGF beta
Th1 primary function
activate macrophages
th2 primary function
activate eosinophils and mast cells
alternative macrophage activation
Th17 primary function
enhance neutrophil response
Tfh primary function
activate and mature B cells
t reg primary function
suppress other effector T. cells
5 types of antibody
IgG
IgE
IgD
IgM
IgA
IgG
multi purpose
high affinity
crosses the placenta
IgE
parasite responses and allergies
IgD
basophils
IgA
secreted at mucus sites
IgM
first to be made on first encounter with antigen