types of T cells and antibodies Flashcards

1
Q

th1 polarising cytokine from APC

A

IL-12

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2
Q

Th2 polarising cytokine from APC

A

IL-4

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3
Q

Th17 polarising cytokine from APC

A

IL-6
IL-21

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4
Q

Tfh polarising cytokine from APC

A

IL-6
TGF beta
IL-23

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5
Q

Treg polarising cytokine from APC

A

TGF beta

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6
Q

Th1 transcription factor

A

T-bet

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7
Q

th2 transcription factor

A

GATA3

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8
Q

Th17 transcription factor

A

ROR gamma T

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9
Q

Tfh transcription factor

A

Bcl6

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10
Q

T reg transcription factor

A

FoxP3

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11
Q

Th1 cytokines produced

A

IFN gamma

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12
Q

Th2 ytokines produced

A

IL-4
IL-5
IL-13

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13
Q

Th17 cytokines produced

A

IL-17
IL-22

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14
Q

Tfh cytokines produced

A

IL-21
IL-4 or IFN gamma

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15
Q

T reg cytokines produced

A

IL-10
TGF beta

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16
Q

Th1 primary function

A

activate macrophages

17
Q

th2 primary function

A

activate eosinophils and mast cells
alternative macrophage activation

18
Q

Th17 primary function

A

enhance neutrophil response

19
Q

Tfh primary function

A

activate and mature B cells

20
Q

t reg primary function

A

suppress other effector T. cells

21
Q

5 types of antibody

A

IgG
IgE
IgD
IgM
IgA

22
Q

IgG

A

multi purpose
high affinity
crosses the placenta

23
Q

IgE

A

parasite responses and allergies

24
Q

IgD

A

basophils

25
Q

IgA

A

secreted at mucus sites

26
Q

IgM

A

first to be made on first encounter with antigen