types of T cells and antibodies Flashcards
th1 polarising cytokine from APC
IL-12
Th2 polarising cytokine from APC
IL-4
Th17 polarising cytokine from APC
IL-6
IL-21
Tfh polarising cytokine from APC
IL-6
TGF beta
IL-23
Treg polarising cytokine from APC
TGF beta
Th1 transcription factor
T-bet
th2 transcription factor
GATA3
Th17 transcription factor
ROR gamma T
Tfh transcription factor
Bcl6
T reg transcription factor
FoxP3
Th1 cytokines produced
IFN gamma
Th2 ytokines produced
IL-4
IL-5
IL-13
Th17 cytokines produced
IL-17
IL-22
Tfh cytokines produced
IL-21
IL-4 or IFN gamma
T reg cytokines produced
IL-10
TGF beta
Th1 primary function
activate macrophages
th2 primary function
activate eosinophils and mast cells
alternative macrophage activation
Th17 primary function
enhance neutrophil response
Tfh primary function
activate and mature B cells
t reg primary function
suppress other effector T. cells
5 types of antibody
IgG
IgE
IgD
IgM
IgA
IgG
multi purpose
high affinity
crosses the placenta
IgE
parasite responses and allergies
IgD
basophils