Type IV Flashcards

1
Q

Graft vs Host disease

A

GVHD
- Immune cells present in donor tissue (the graft) attack host’s own tissues

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1
Q

Type IV

A

Delayed hypersensitivity
- Mediated by T cell lymphocytes
> do not involve antibody
- 12-72 hours after exposure to antigen
> EX: TB test, posion ivy, graft vs host

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2
Q

Delayed Hypersensitivity - CMs

A
  • Skin rash
  • Jaundice
  • GI distress
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3
Q

Delayed Hypersensitivity - Medications

A
  • Immunosuppressive meds are primary therapy
    > prednisone, cellcept
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