Immunodeficiency Disorders: Primary

Question 1

Immunodeficiency Disorders - Primary

Answer 1

• Rare, genetic cause
  > male:female 5:1
• Usually dx in infants/toddlers
  > some adolescence/young adults
• Often accompany autoimmune disorders
• Common Types
  > Antibody deficiency
  > Phagocytic dysfunction
  > B cells or T cells (of both) defects
  > Complement system deficiency

Question 2

Immunodeficiency Disorders - Primary: CMs

Answer 2

• Severe/recurrent infections
• Failure to thrive
• Positive fam hx

Question 3

Immunodeficiency Disorders - Primary: Medical Treatment

Answer 3

• Antibiotics: infection/prophylactic
• IVIG: (IV immunoglobulin) or SQ
• Hematopoietic Stem Cell Transplant
  > curative
• No live vaccines
• Genetic counseling