Type 2 DM Flashcards
what is always first line for DM 2?
lifestyle changes
entrance a1c is below 7.5%
monotherapy metformin
entrance a1c is above 7.5%
dual therapy: metformin plus either GLP-IRA, SGLT-2i or DDP 4
OR
triple therapy: metformin + GLP1RA, SGLT2i or TZD or basal
in order to figure out what is next treatment step if patient has entrance a1c of over 9% what question do you need to ask?
do you have symptoms?
a1c over 9% with sx
add an insulin to current treatment plan
a1c over 9% without sx
step therapy up to dual or triple
examples of GLP1 agonists
liraglutide, exenatide, albiglutide, lixisenatide, dulaglutide
DPP4 inhibitor examples
sitagliptin, linagliptin, saxagliptin, alogliptin
Thiazolidindione exampels
pioglitazone, rosiglitazone
sulfonylurea examples
glipizide, glyburide, glimepiride
meglitinides examples
repaglinide, nateglinide
alpha glucosidase inhibitor examples
acarbose, miglitol
sodium glucose cotransporter 2 inhibitors
canagliflozin, dapaglicozen, empaglifozen