Type 2 Diabetes Flashcards

1
Q

Pre-Diabetes (Metabolic Syndrome)

A

Independently raises the risk of developing

type 2 diabetes and cardiovascular disease

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2
Q

Diabetes Prevention Program (DPP)

—- losing 5 to 7% of body
weight by making healthy food choices and being physically active 30 min a day, 5 days a week reduced onset of type 2 diabetes by ____%

A

58%

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3
Q

Diabetes—Can lead to serious problems and complications, such as heart disease, blindness, kidney failure, lower limb
amputations, and premature death

A

KNOW

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4
Q

Common Types of Diabetes

Type 1 Diabetes Mellitus

Auto-immune disease
• Develops when immune system destroys
_________ __________ cells = the only cells in the body that make insulin which regulates blood glucose
• Usually affects CHILDREN and young adults, although may occur at any age
• 5% to 10% of diagnosed cases of diabetes

A

pancreatic beta

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5
Q

Common Types of Diabetes

Gestational Diabetes Mellitus

Occurs during PREGNANCY
Women who have had gestational
diabetes have an increased LIFELONG risk
\_\_\_\_\_\_\_\_\_\_ are also at higher risk for
obesity and type 2 diabetes compared
to other children
• 40% to 60% women with gestational diabetes will develop diabetes in the next 5 to 10 years
A

Offspring

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6
Q

Common Types of Diabetes

Type 2 Diabetes Mellitus

Usually begins as insulin resistance
• Given concentration of insulin produces a less-than expected biological response
—-Often described interchangeably with ___________ _____________
• As the need for insulin rises, the ___________ gradually loses its ability to produce insulin
• Insulin resistance and ABNORMAL ____ _______ function may occur long before type 2 diabetes is diagnosed
• 90% to 95% of diagnosed cases of diabetes

A

Metabolic Syndrome

pancreas

beta cell

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7
Q

Type 2 Diabetes Risk Factors

• Elevated _________ __________
measurement of ≥ 140/90 mm/Hg
• Abnormal _______ _________
HDL cholesterol

A

Blood pressure

lipid levels

vascular

Impaired Glucose Tolerance

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8
Q

Diabetes Complications

• Diabetes is the leading cause of _________ __________
- accounts for 44% of new cases
• Leading cause of new cases of _______ ____________
- accounts for 12,000 to 24,000 cases every year
• Leading cause (> 60%) of non-traumatic lower limb ____________
• 2 to 3X greater risk of periodontal, or gum disease
• 60 to 70 % of adults with diabetes have mild to severe ________ system damage

A

Kidney failure

adult blindness

amputations

nervous

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9
Q

CVD is the leading cause of death for people
with diabetes

_______ _________ is key to preventing or delaying complications of diabetes
Any sustained lowering of blood glucose helps, even if the person has a history of poor control

A

Glucose control

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10
Q

Hemoglobin A1c (HbA1c)

–Represents the glycosylation (or glycation) of __________ in red blood cells
—Reflects average blood sugar for past 2 to 3 months
— Long-term measure of glucose control
Each 1% decrease in annual mean A1C level
reduced risk of:
• Microvascular complications by 37%
• Peripheral vascular disease (PVD) by 43%
• Myocardial infarction (MI) by 14%
• Stroke by 12%
• Heart failure by 16%
• Cataract extraction by 19%

A

hemoglobin

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11
Q

Principle goal of nutritional management
for ALL people with diabetes:

  1. Maintaining normal or near normal SERUM GLUCOSE levels (glycemia)
  2. Prevent and reverse LIPID abnormalities
    (dyslipidemia)
  3. Maintain/improve BLOOD PRESSURE (hypertension)

A is for A1C
B is for Blood Pressure
C if for Cholesterol

A

KNOW

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12
Q

+1—General Recommendations

 No “___________” diabetes eating pattern
 EDUCATE patient about nutrition and lifestyle
 Build patients sense of self-efficacy for
self-care
 Emphasize nutrient-dense foods in reasonable portions
 Maintain the pleasure of eating!
 Provide practical tips for daily _____ _____ and _________ instead of worrying too much about individual macronutrients and micronutrients

A

one-size-fits-all

meal prep

planning

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13
Q

2—General Recommendations

—–Increase FIBER intake
NOTE: >50 g/day of fiber reported to improve
_______ in persons with diabetes
—Adding PROTEIN to bedtime snacks is often recommended to prevent overnight ________

–Type of fatty acids consumed is more important than
total fat

“Consumption of _________ is associated with a statistically significant decrease in levels of fasting plasma glucose, total cholesterol, LDL-C, and triglyceride levels, and an increase in HDL-C levels”

Magnesium deficiency common

A

glycemia

hypoglycemia

cinnamon

No specific “diabetes diet” exists

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14
Q

Recent studies suggest ________ restriction may NOT be beneficial:

“For people with diabetes and diabetic kidney disease (either micro- or macroalbuminuria), reducing the amount of dietary protein below the usual intake is NOT recommended because it does NOT alter glycemic measures, cardiovascular risk measures, or the course of glomerular filtration rate (GFR) decline

A

protein

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15
Q

Low Glycemic Index/Load Diet

—–“Choosing low-GI foods in place
of conventional or high-GI foods has a small but clinically useful effect on medium-term glycemic control in patients with diabetes”

A

KNOW

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16
Q

Weight Loss (Body fat loss)

  • —For majority of diabetics, WEIGHT LOSS and maintenance are the principal clinical management tool
  • –Significant reduction of cardiometabolic risk factors can be expected with 7 – 10 % weight loss in the obese patient
A

KNOW

17
Q

_______ ________ alone NOT enough
Does NOT always lead to improvements in HbA1c, LIPIDS or ______ ________ – most beneficial EARLY in diagnosis
• _________ ________ required
(nutrition, physical activity, and other behavior change)
—Intensive lifestyle intervention resulted in “partial or complete remission of diabetes”

A

Weight loss

blood pressure

Lifestyle change

18
Q

Hypoglycemia

Serum glucose level

A

50

mental

DEATH

neuronal damage

19
Q

Neuropathy

1—Chronic high levels of blood glucose are associated with nerve damage and affects 60-70% of patients with both type 1 and type 2 diabetes

___________ neuropathy affect sensation in hands and feet
___________ neuropathy affects nerves controlling various organ systems

2—CV effects include decreased responsiveness to _______ nerve impulses leading to painless or silent, ischemic
heart disease

3—Can impact nerves in ___ ______ – can manifest as nausea or esophagitis, unpredictable stomach emptying, in
large bowel as diarrhea or constipation etc.

A

Peripheral

Autonomic

cardiac

GI tract

20
Q

Alpha-lipoic acid, Evening primrose oil, and
capsaicin have received the greatest attention for their use in DIABETIC
neuropathy

A

KNOW

21
Q

Evening Primrose Oil— improved nerve function measurements

  • –Is an essential component of myelin and the neuronal cell membrane
  • —Includes omega __ essential fatty acids: gamma linoleic acid (GLA) and linoleic acid
A

6

22
Q

Alpha-Lipoic Acid (LA)
(aka lipoic acid or thioctic acid)

—An __________ found in foods such as liver, spinach, broccoli, and potatoes
• Researched for its effect on insulin sensitivity, glucose metabolism, and diabetic neuropathy
—Oral LA supplements are better absorbed on an empty stomach than with food

***NOTE: LA might lower _____ ________ too much, so people with
diabetes who take it must monitor
their blood sugar levels very
carefully

A

antioxidant

blood sugar

23
Q

Chromium

An essential trace mineral found in many foods, but usually only in small amounts; relatively good sources include meat, whole grain products, and some fruits, vegetables, and spices
• Well established cofactor in _______ metabolism
• Researched for its effect on glucose control in diabetics
• Evidence is NOT conclusive
—Low doses: short-term use of chromium appears to be safe for most adults however,
• High doses: may cause serious side effects, including kidney problems – do NOT use with kidney disease

A

insulin

24
Q

Omega-3 fatty acids

1—Studies show that omega-3 fatty acids lower triglycerides, but do NOT affect blood glucose control, total cholesterol, or ____ in people with diabetes

A

HDL

25
Q

Polyphenols

1–Laboratory studies suggest that Epigallocatechin gallate (EGCG) a polyphenol found in ____ _______, may protect against cardiovascular disease and have a
beneficial effect on insulin activity and glucose control

A

green tea

26
Q

Food for Thought….

Addressing the Root Cause:
Diabetes, elevated blood sugar, blood pressure, and cholesterol = Appear to be downstream symptoms resulting from underlying problems with diet, lifestyle, stress, exposure to environmental toxins
interacting with our unique genetic susceptibilities

Management plan should address these
underlying causes, NOT just ____________ of symptoms

A

treatment