Type 2 Diabetes Flashcards
1
Q
Pathophysiology
A
Insulin resistance
2
Q
Risk factors
A
Obesity
Increasing age
Sedentary lifestyle
High Glycaemic index diet
Black African
FHx
3
Q
Symptoms
A
Polydipsia
Polyuria
Fatigue
Weight loss
Poor wound healing
4
Q
Diagnosis
A
2X Hba1C > 6.5%
Fasting glucose > 7 mmol
Random glucose > 11.1 mmol
5
Q
Management
A
Dietary control
Weight loss
Exercise
Manage complications
Drug treatment
6
Q
Drug treatment
A
Metformin
Add ACEi if HTN
Add GLP-1 if BMI>35
Add SGLT-2 if HF
7
Q
Drug side effects
A
Metformin - GI, AKI
SGLT-2 - Thrush, UTI, DKA, Frequency
PPAR - Risk bladder cancer, fractures, weight gain
SU - Wight gain, Risk Hypo
Gliptin - Acute pancreatitis, Headaches
GLP - Reduced appetite
8
Q
Complications
A
Eyes
Feet
CVS
CKD -> ACEi
Neuropathy -> Amitriptyline
HSS -> IV Fluids
ED -> Sildenafil
