Cushing's Syndrome Flashcards

1
Q

Condition

A

Excess Cortisol

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2
Q

Causes

A

Pituitary adenoma
Adrenal adenoma
Ectopic (SCC)
Excess steroid tablets

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3
Q

Investigations

A

24 hour urinary cortisol
Serum ACTH
Dexamethasone suppression test

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4
Q

Symptoms

A

Abdominal distention
Weight gain
Thin extremities
Abdominal Striae
Moon face
Buffalo hump

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5
Q

Lab findings

A

Hypernatremia
Hypokalemia

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6
Q

Dexamethasone suppression test findings

A

Pituitary - Supressed with high dose
Ectopic - Unsuppressed, High ACTH
Adrenal - unsuppressed, Low ACTH

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7
Q

Cause investigations

A

MRI Head
CT Chest
CT Adrenals

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8
Q

Treatment

A

Remove tumour
If unable to remove tumour remove adrenals

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9
Q

Steroid rules

A

2x if unwell
Take again if D/V within 1 hour
Carry steroid alert card/ Bracelet

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