Adrenal insufficiency Flashcards

1
Q

Pathophysiology

A

Reduced Aldosterone, Cortisol , Androgens

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2
Q

Causes

A

Primary - Addison’s (Adrenal)
Secondary - Pituitary tumour
Tertiary - Steroid withdrawal

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3
Q

Investigations

A

Short Synacthen test - Cortisol should double
Serum cortisol
Give ACTH
Serum cortisol 30 min
Serum cortisol 60 min

Serum ACTH
High in primary, Low in secondary

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4
Q

Labs

A

Hyponatremia
Hyperkalaemia
Acidosis

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5
Q

Symptoms

A

Weakness
Fatigue
Hyperpigmentation if Addison’s - Creases, Lips, Buccal Mucosa
Craving Salt
Thirst

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6
Q

Adrenal crisis signs

A

Hyponatraemia
Hypotensive
Decreased consciousness

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7
Q

Adrenal crisis triggers

A

Infection
Trauma

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8
Q

Treatment

A

Fludrocortisone, Hydrocortisone
Steroid card/ ID Tag
Educate how to administer IM Hydrocortisone

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9
Q

Crisis Treatment

A

IV Fluids
IV Hydrocortisone
Correct BM/K/Na

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