Two Phase System Mixtures Flashcards
Aqueous liquid preparation which contains
suspended (suspensoid),
insoluble,
solid substance
Mixtures
Particle size of mixtures
Particle size > 0.5 µm
The insoluble substance may be held in suspension by the use of suitable suspending or thickening agent since the insoluble substance does not make the mixture very viscous.
Mixture
Must be in a very finely divided state
and it must be uniformly distributed throughout the preparation
Insoluble substance
Very finally divided state (insoluble substance) is accomplished by the use of :
- Colloid Mills
- Special method if precipitation and suspending agent
There is a need of suspending or thickening agent since the insoluble substance does not make the mixture very viscous
Mixture
Reasons for having the insoluble substance in the finer state of subdivision
- The more active they become as adsorbent and protectives when in contact with the inflamed areas
- ** suspended more readily and settle out much slowly** than large particles, thus enabling the patient to obtain uniform doses of suspended particle
- To increase palatability of the preparation with the use of colloidal suspending agent
Size of lotion
Colloidal dispersion between 1.0 nm and 0.5 µm
Particle size of magma and gel
0.5 µm to 10 µm
Particle size of mixture
> 0.5 µm
Rapid diffusion, invisible in electron microscope
Ordinary ions
<1.0nm
Molecular dispersion
Diffuse slowly visible in electron microscope, ultra microscope
Colloidal Ag sol
1.0nm — 0.5 µm
Colloidal dispersion
Don’t diffuse visible under microscope
Suspension and Emulsion
> 0.5 µm
**Coarse dispersion **
Category of chalk mixture
Medicated mixture
Synonyms of chalk mixture
Mixture de Creta
Mistura Cratae