Tumours Flashcards

1
Q

What is the most common brain tumour

A

metastases

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2
Q

What is a grade 1 astrocytoma called

A

pilocytic astrocytoma

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3
Q

Who gets pilocytic astrocytomas

A

kids and young adults

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4
Q

pilocytic astrocytomas are benign/malignant

A

benign

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5
Q

With which brain tumour is neurofibromatosis 1 associated

A

grade 1 pilocytic astrocytoma

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6
Q

what is the management of grade 1 brain tumours

A

surgical resection is curative

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7
Q

what is a grade 2 astrocytoma called

A

fibrillary astrocytoma

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8
Q

grade 2 brain tumour is low/high grade, benign/malignant

A

low grade

malignant

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9
Q

grade 2 fibrillary astrocytoma can dedeifferentiate into a high grade malignancy, true or false

A

true

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10
Q

radiotherapy is never given to under 3 year olds, true or false

A

true

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11
Q

grade 2 astrocytomas can be cured, true or false

A

false

tumour will inevitably return, it is just a question of when

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12
Q

what is a grade 3 astrocytoma called

A

anaplastic astrocytoma

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13
Q

which age group is affected by anaplastic astrocytomas

A

30-50 y/o

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14
Q

what is a grade 4 astrocytoma called

A

glioblastoma multiforme

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15
Q

what is the most common primary brain tumour in 60-75 year olds

A

glioblastoma multiforme

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16
Q

what are the management options for brain tumours

A

surgery
chemotherapy: temozolamide, procarbazine, vincristine, carmustine
radiotherapy
immunotherapy

17
Q

what are side effects of brain radiotherapy

A

drops IQ
hair loss
skin thinning

18
Q

what do oligodendrocytomas arise from

A

oligodendrocytes

19
Q

How do patients with oligodendrocytomas present

A

seizures

20
Q

how do children with oligodendrocytomas present

A

vomiting and headaches

tiptoe walking

21
Q

buzzwords for oligodendrocytomas

A

greyish pink

toothpaste like

22
Q

what cells do meningiomas arise from

A

arachnoid cap cells

23
Q

what bodies are found in meningiomas

A

psammoma bodies

24
Q

meningiomas are benign/malignant

A

benign

25
Q

how can meningiomas present

A

asymptomatic - incidental
headaches
seizures
CN palsies

26
Q

describe radiation induced meningioma

A

meningioma found in midline after radiotherapy treatment in childhood

27
Q

what is pre operative embolisation

A

embolisation of a vascular tumour before operating

28
Q

what is the management of small meningiomas

A

conservative

29
Q

meningiomas and pregnancy?

A

they grow due to oestrogen

30
Q

what does surgical resection of meningiomas involve

A

removal of the tumour and associated dura mater to decrease chance of recurrence

31
Q

example of malignant nerve sheath tumour

A

acoustic neuroma / vestibular schwannoma

32
Q

what tumour is neurofibromatosis 2 associated with

A

vestibular schwannomas (esp bilaterally)

33
Q

what sign in seen on imaging with acoustic neuromas

A

ice cream cone sign on MRI

34
Q

What syndrome can pineal tumours cause

A

Parinauds syndrome
upward gaze palsy
pupillary light near dissociation
conversion retraction nystagmus

35
Q

what can pineal tumours compress

A

extra ocular muscles

36
Q

what should be suspected if there is a midline tumour in a child

A

germ cell tumours

37
Q

what is the most important examination to do if a brain tumour is suspected

A

fundoscopy