Tumour Suppressor genes and oncogenes Flashcards
1
Q
p53
A
Tumour suppressor
Common to many cancers
Chromosone 17p
Li-fraumeni
2
Q
APC
A
Tumour suppressor Colorectal cancer
3
Q
BRCA1
A
Tumour suppressor Breast and ovarian cancer
4
Q
BRCA2
A
Tumour suppressor Breast and ovarian cancer
5
Q
RAS
A
Oncogene
G-protein
Many cancers especially pancreatic
6
Q
erb-B2 (HER2/neu)
A
Oncogene
Tyrosine kinase receptor
Breast and ovarian cancer
7
Q
c-MYC
A
Oncogene
Burkitt’s lymphoma