Tumour Suppressor genes and oncogenes Flashcards

1
Q

p53

A

Tumour suppressor
Common to many cancers
Chromosone 17p
Li-fraumeni

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2
Q

APC

A

Tumour suppressor Colorectal cancer

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3
Q

BRCA1

A

Tumour suppressor Breast and ovarian cancer

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4
Q

BRCA2

A

Tumour suppressor Breast and ovarian cancer

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5
Q

RAS

A

Oncogene
G-protein
Many cancers especially pancreatic

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6
Q

erb-B2 (HER2/neu)

A

Oncogene
Tyrosine kinase receptor
Breast and ovarian cancer

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7
Q

c-MYC

A

Oncogene

Burkitt’s lymphoma

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