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Quick Revision > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

What are the two divisions of antibiotics that work on DNA replication?

A

Fluoroquinolones and Metronidazole

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2
Q

Name two broad spectrum fluoroquinolones

A

Levofloxacin and Ciprofloxacin

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3
Q

What is the mechanism of antibiotics that prevent RNA synthesis?

A

RNA polymerase inhibitor

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4
Q

Name some RNA polymerase inhibitor drugs?

A

Rifampicin
Fidaxomicin
Anti-TB drugs

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5
Q

What three classes of antibiotics prevent protein synthesis?

A

Macrolides
Aminoglycosides
Tetracyclines

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6
Q

Name a macrolide antibiotic?

A

Clarithromycin

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7
Q

Name an aminoglycoside antibiotic

A

Gentamicin

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8
Q

Name a tetracycline antibiotic

A

Doxycycline

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9
Q

What classes of antibiotics work against cell wall synthesis?

A

Vancomycin

B-Lactams

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10
Q

What are the three types of B-lactam antibiotics?

A

Penicillins
Cephalosporin
Carbapenem

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11
Q

What are the three classes of penicillins?

A

Broad
B-lactamase resistant
Extended spectrum

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12
Q

Name some broad spectrum penicillins

A

Amoxicillin

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13
Q

Name a B-lactamase resistant penicillin

A

Flucloxacillin

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14
Q

Name an extended spectrum penicillin

A

Piperacillin

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15
Q

Name two 3rd generation cephaloporins

A

Cefotaxime

Ceftazidime

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16
Q

Name two carbapenem

A

Meropenem

Imipenem

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17
Q

Name an antibiotic that prevents folate synthesis

A

Trimethoprim
Sulphonamide
(Co-trimoxazole)

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18
Q

What is the treatment for pneumococcal pneumonia?

A

Amoxicillin
Benzyl penicillin
Cephalosporin

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19
Q

What is the treatment for staphylococcal pneumonia?

A

Flucloxacillin

Rifampicin

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20
Q

What is the treatment for klebsiella pneumonia?

A

Cefotaxime or imipenem

21
Q

What is the treatment for pseudomonas pneumonia

A

Anti-pseudomonal penicillin, ceftazidime, meropenem or ciprofloxacin and aminoglycoside

22
Q

What is the treatment for mycoplasma pneumonia?

A

Clarithromycin or doxycycline or a fluoroquinolone

23
Q

What is the treatment for legionella pneumonia?

A

Fluoroquinolone or clarithromycin

24
Q

What is the treatment for chlamydophilia psittaci?

A

Doxycycline or clarithromycin

25
Q

What is the treatment for pneumocystis pneumonia?

A

High dose co-trimoxazole or pentamidine IV

26
Q

What is the treatment for severe proven spontaneous bacterial peritonitis?

A

Piperacillin/Tazobactam
Then
Co-trimoxazole

27
Q

What is the treatment for mild proven spontaneous bacterial peritonitis?

A

Co-trimoxazole

28
Q

What is the treatment for non-severe C. diff?

A

Metronidazole

29
Q

What is the treatment for severe C. diff?

A

Vancomycin +/- Metronidazole

30
Q

What is the treatment for recurrent C. diff?

A

Fidaxomicin

31
Q

What is the treatment for Native valve indolent (subacute) endocarditis?

A

Amoxicilllin Gentamicin

32
Q

What is the treatment for Native valve severe sepsis (acute) endocarditis?

A

Flucloxacillin

33
Q

What is the treatment for Prosthetic valve MRSA endocarditis?

A

Vancomycin Rifampicin Gentamicin

34
Q

What is the treatment for Native valve severe sepsis and risk factors of specific resistance endocarditis?

A

Vancomycin Meropenem

35
Q

What is the treatment for enterococcus endocarditis?

A

Amoxicillin Vancomycin Gentamicin

36
Q

What is the treatment for Viridans endocarditis?

A

Penicillin Gentamicin

37
Q

What is the treatment for IV drug user endocarditis?

A

Flucloxacillin

38
Q

What is the treatment for Epidermidis endocarditis?

A

Vancomycin Gentamicin

39
Q

What is the treatment for peritonitis/biliary/intra-abdominal?

A

IV Amoxicillin Metronidazole Gentamicin
Then
PO Co-trimoxazole Metronidazole

40
Q

What is the 1st line treatment for an acute exacerbation of COPD?

A

Amoxicillin 500mg tds

41
Q

What is the 2nd line treatment for an acute exacerbation of COPD?

A

Doxycycline 200mg day one then 100mg (5 days)

42
Q

What is the 1st line treatment for acute cough/bronchitis?

A

Amoxicillin 500mg tds

43
Q

What is the 2nd line treatment for acute cough/bronchitis?

A

Doxycycline 200mg day one then 100mg after

44
Q

What is the treatment for mild/moderate CAP?

A

Amoxicillin (IV/PO 5 Days)

If penicillin allergic Doxycycline

45
Q

What is the treatment for severe CAP?

A

Co-amoxiclav IV + Doxycycline PO

*If penicillin allergic Levofloxacin

46
Q

What is the treatment for ICU/HDU CAP?

A

Co-amoxiclav IV + Clarithromycin IV
Then
Doxycycline
*If penicillin allergic Levofloxacin

47
Q

What is the treatment for severe HAP?

A

IV Amoxicillin+ Metronidazole + Gentamicin
Step down to PO Co-trimoxazole + Metronidazole

*If penicillin allergic IV Co-trimoxazole + Metronidazole +/- Gentamicin

48
Q

What is the treatment for non-severe HAP?

A

PO Amoxicillin + Metronidazole

*If penicillin allergic PO Co-trimoxazole + Metronidazole

Quick Revision (20 decks)

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